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SEED version cvs.1555556707 (3/17/2019 22:5:7) on gum.mcs.anl.gov
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Protein fig|93062.19.peg.2133: Staphylococcus aureus subsp. aureus COL

This feature in The SEED Viewer

NCBI Taxonomy Id: 93062

Current Assignment: NAD-dependent protein deacetylase of SIR2 family
Translate Function Assignments


Context on contig NC_002951 from base 2263934 to 2276649 (12716 bp)

Fid Start End Size
(nt)		   Gap Find
best
clusters		 Pins Fc-sc SS Ev Function Aliases
2126 2265295 2263934 1362 -           PTS system, lactose-specific IIB component (EC 2.7.1.69) / PTS system, lactose-specific IIC component (EC 2.7.1.69) gene_name|lacE, locus|SACOL2181, protein_id|YP_186992.1, gi|57650777, geneID|3238567
2127 2265963 2265652 312 - 356       dlit(4096897)
dlit(7306504)
dlit(2824493)
dlit(1881873)
dlit(7138836)		 PTS system, lactose-specific IIA component (EC 2.7.1.207) gene_name|lacF, locus|SACOL2182, protein_id|YP_186993.1, gi|57650778, geneID|3238568
2128 2266965 2265985 981 - 21       dlit(2543958)
dlit(1655695)		 Tagatose 1,6-bisphosphate aldolase (EC 4.1.2.40) gene_name|lacD, locus|SACOL2183, protein_id|YP_186994.1, gi|57650779, geneID|3238060
2129 2267901 2266969 933 - 3         Tagatose-6-phosphate kinase (EC 2.7.1.144) gene_name|lacC, locus|SACOL2184, protein_id|YP_186995.1, gi|57650780, geneID|3238197
2130 2268429 2267914 516 - 12         Galactose-6-phosphate isomerase, LacB subunit (EC 5.3.1.26) gene_name|lacB, locus|SACOL2185, protein_id|YP_186996.1, gi|57650781, geneID|3238198
2131 2268873 2268445 429 - 15       dlit(2163387) Galactose-6-phosphate isomerase, LacA subunit (EC 5.3.1.26) locus|SACOL2186, protein_id|YP_186997.1, gi|57650782, geneID|3238604
2132 2269996 2269241 756 - 367         Lactose phosphotransferase system repressor gene_name|lacR, locus|SACOL2188, protein_id|YP_186999.1, gi|57650784, geneID|3238563
2133 2270247 2270978 732 + 250     5: 1 2 3 4 5   NAD-dependent protein deacetylase of SIR2 family locus|SACOL2189, protein_id|YP_187000.1, gi|57650785, geneID|3238564
2134 2271015 2271176 162 + 36         FIG01107911: hypothetical protein  
2135 2271877 2271269 609 - 92         FIG01108842: hypothetical protein locus|SACOL2190, protein_id|YP_187001.1, gi|57650786, geneID|3238090
2136 2272264 2272139 126 - 261         Doubtful CDS. No database matches locus|SACOL2191, protein_id|YP_187002.1, gi|57650787, geneID|3238091
2137 2273332 2272484 849 - 219         Oxidoreductase of aldo/keto reductase family, subgroup 1 locus|SACOL2192, protein_id|YP_187003.1, gi|57650788, geneID|3238569
2138 2273818 2273402 417 - 69         Transcriptional regulator, MerR family locus|SACOL2193, protein_id|YP_187004.1, gi|57650789, geneID|3238570
2139 2274226 2276649 2424 + 407         Hyaluronate lyase precursor (EC 4.2.2.1) gene_name|hysA, locus|SACOL2194, protein_id|YP_187005.1, gi|57650790, geneID|3238658

Annotation History   /   View All Related Annotations Help on Annotations


  Subsystems in Which This Protein Plays a Role

Subsystem Curator Role
Redox-dependent_regulation_of_nucleus_processes OlgaV NAD-dependent protein deacetylase of SIR2 family
Pyruvate_metabolism_II:_acetyl-CoA,_acetogenesis_from_pyruvate SvetaG NAD-dependent protein deacetylase of SIR2 family
sirtuins nguyen_hong_user NAD-dependent protein deacetylase of SIR2 family
Cobalamin_(Wirth) Wirth_Joe_user NAD-dependent protein deacetylase of SIR2 family
NAD_and_NADP_cofactor_biosynthesis_global AndreiO *NAD-dependent protein deacetylase of SIR2 family


  Protein Sequence

>fig|93062.19.peg.2133 NAD-dependent protein deacetylase of SIR2 family
MKHDLETLKHIIDSSNRITFFTGAGVSVASGVPDFRSMGGLFDEISKDGLSPEYLLSRDY
LEDDPEGFINFCHKRLLFVDTMPNIVHDWIAKLERNQQSLGIITQNIDGLHSDAGSQHVD
ELHGTLNRFYCNVCHKSYTKSDVIDRTLKHCDNCGGAIRPDIVLYGEMLDQPTIIRALNK
IEHADTLVVLGSSLVVQPAAGLISHFKGDNLIIINKDRTPYDSDATLVIHDDMVSVVKSL
MTE

MD5 = 9dc2aca2485b44077cd840e1682686a4


  DNA Sequence

>fig|93062.19.peg.2133 NAD-dependent protein deacetylase of SIR2 family
ttgaaacatgatttagagacactaaaacatattatagatagttcgaatcgtattacattt
tttacaggtgctggtgtatctgtcgcaagtggcgttccagatttccgttcaatgggtggc
ttatttgatgaaatttcaaaagatgggctttcgccagaatacttgttaagccgtgattat
ttagaagatgatcctgaaggttttatcaatttctgccataagcgcttactatttgtcgat
acgatgcccaatatcgttcatgattggattgcaaaattagaacgtaatcaacaatcttta
ggtatcatcacgcaaaatatcgatggtttgcactcagacgctggaagtcaacatgttgat
gaattacatggcacgttaaatcgtttttattgtaatgtatgtcataaatcttatacgaag
tcagatgttattgatagaactttgaaacattgtgataattgtggtggtgccattcgaccg
gacatcgtattatacggtgaaatgttagatcaacctaccatcataagggcattaaataaa
attgaacatgctgacacccttgttgtactaggttcatcactcgttgtacaacctgccgca
ggattaatatcacattttaaaggcgacaatttaattattatcaataaagatcgaacacct
tatgatagcgacgctactttggtcatacatgacgacatggtttccgttgtaaaatcatta
atgacagagtaa


  DNA with Flanking Sequence

>fig|93062.19.peg.2133 NAD-dependent protein deacetylase of SIR2 family
ctataaatcgtttttctgcaatttgacgggtatgtttttctttatgcgatatttctttat
actgaaatgttgaattactgcgtgcaccaccatgaatcttcgttaaaatccctttatttt
ccaattcaattaaatctcttcgaactgtcatatcagacacatttaaaccttcgacgattt
cattcgttcttatcgtgccctttttattcactagtttagcaatttcgtccaaacgttcat
gtttattcaatgtaaaattgcctcctttatttaggcgatgggtcattatcctttatgttt
agacatcaattttaatatacatgcttattctataataaaaattgcgtaaaaactaatata
atttaactgttcgattatatgtataattcatttttaaaaagaactgtttaaactgcgctt
ttgataatcgtaaaatgaatatactataataaaagtaaaagacgttataaatcattcatt
attttgatggggtgtttaacttgaaacatgatttagagacactaaaacatattatagata
gttcgaatcgtattacattttttacaggtgctggtgtatctgtcgcaagtggcgttccag
atttccgttcaatgggtggcttatttgatgaaatttcaaaagatgggctttcgccagaat
acttgttaagccgtgattatttagaagatgatcctgaaggttttatcaatttctgccata
agcgcttactatttgtcgatacgatgcccaatatcgttcatgattggattgcaaaattag
aacgtaatcaacaatctttaggtatcatcacgcaaaatatcgatggtttgcactcagacg
ctggaagtcaacatgttgatgaattacatggcacgttaaatcgtttttattgtaatgtat
gtcataaatcttatacgaagtcagatgttattgatagaactttgaaacattgtgataatt
gtggtggtgccattcgaccggacatcgtattatacggtgaaatgttagatcaacctacca
tcataagggcattaaataaaattgaacatgctgacacccttgttgtactaggttcatcac
tcgttgtacaacctgccgcaggattaatatcacattttaaaggcgacaatttaattatta
tcaataaagatcgaacaccttatgatagcgacgctactttggtcatacatgacgacatgg
tttccgttgtaaaatcattaatgacagagtaatcagtatgtaaaaagcatttcccgaatg
gtagggaaatgcttttaattttggagttgcgtttttggaatttggagtttggttttcgga
attcgacatttggaattcagaattataatgagtggaaaattttaattattgcgtgtttaa
tgacttggttttgtagcgatttttatttgatgaattgtttttttgtttgatgttgggatg
ctacttttaatggtttgtcatttgtaagattaaaaataaacataaaataagtagaaaaat
aaaagctacgaatattaaaaaattagatatcttcattatcaaattccgatattaaatcat
tatatttttcagaatatcttgcataatcttcattattattaaaagctagccatagacctc
tatcatcatataaatgatatattaagtttttagtattgttaattatatatatttcagaat
aattatcattctgattgatatttggaactaaccctttaaagtcttgattgga


  Assignments for Essentially Identical Proteins

Id Organism Who ASSIGN Assignment
GO:0005737       C:cytoplasm
GO:0006342       P:chromatin silencing
GO:0006476       P:protein amino acid deacetylation
GO:0008270       F:zinc ion binding
GO:0016811       F:hydrolase activity, acting on carbon-nitrog...
GO:0070403       F:NAD binding
cmr|SACOL2189 Staphylococcus aureus subsp. aureus COL     transcriptional regulator, Sir2 family
fig|93062.4.peg.2217 Staphylococcus aureus subsp. aureus COL FIG   NAD-dependent protein deacetylase of SIR2 family
gb|AAW37065.1 Staphylococcus aureus subsp. aureus COL     transcriptional regulator, Sir2 family
gi|57284971 Staphylococcus aureus subsp. aureus COL NCBI   transcriptional regulator, Sir2 family
gi|57650785 Staphylococcus aureus subsp. aureus COL NCBI   NAD-dependent deacetylase
gi|76363270 organism not parsed/found in ncbi nr NCBI   RecName: Full=NAD-dependent deacetylase; AltName: Full=Regulatory protein SIR2 homolog
img|637152953 Staphylococcus aureus aureus COL IMG   transcriptional regulator, Sir2 family
kegg|sac:SACOL2189 Staphylococcus aureus subsp. aureus COL KEGG   NAD-dependent deacetylase
ref|YP_187000.1 Staphylococcus aureus subsp. aureus COL RefSeq   NAD-dependent deacetylase
sp|NPD_STAAC organism not parsed/found in ncbi nr SwissProt   RecName: Full=NAD-dependent deacetylase; AltName: Full=Regulatory protein SIR2 homolog
sp|Q5HE07 Staphylococcus aureus (strain COL) SwissProt   NAD-dependent deacetylase


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  Attributes

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