Annotation Overview for fig|158878.1.peg.1906 in Staphylococcus aureus subsp. aureus Mu50:
Heptaprenylglyceryl phosphate synthase (EC 2.5.1.n9)

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current assignment	Heptaprenylglyceryl phosphate synthase (EC 2.5.1.n9)
taxonomy id	158878	contig	NC_002758 (2,878,040bp)NC_002774 (25,107bp)
internal links	genome browser | feature evidence | sequence	ACH Annotation Clearinghouse (ACH) The Annotation Clearinghouse offers a mapping of genes which are identical in sequence except for the start region (due to differences in start calling). [?]	show essentially identical genes
PubMed links	21761520 24684232
annotation history		run tool	Psi-BlastTMpredTMHMMGram negative PSORTGram negative SignalPGram positive PSORTGram positive SignalPLipoPRadarPPSearchGram negative CELLOGram positive CELLOProDomPDBRNAFold
CDD link	show cdd
PATtyfam	PGF_00011542: Heptaprenylglyceryl phosphate synthase (EC 2.5.1.n9) PLF_1279_00001246: Heptaprenylglyceryl phosphate synthase (EC 2.5.1.n9)
coregulated with	862 pegs
edit functional role	Heptaprenylglyceryl phosphate synthase (EC 2.5.1.n9)
aliases	GeneID:1121919 NP_372430.1 SAV1906 gi|15924896 pcrB	propagation lock	Unlocked Toggle lock

Annotation History (history of similar genes)

Date	Annotator	Annotation
9/2/2005	annotation_repair	Annotation for existing assignment PcrB protein homolog
9/2/2005	annotation_repair	Set master function to PcrB protein homolog
1/20/2007	gjo	Set master function to (S)-3-O-geranylgeranylglyceryl phosphate synthase
10/10/2011	annotation_transfer	Migrating 1 annotations for fig|158878.1.peg.1906 from anno-3 seed (including function assignment) at 2011-10-11 03:16:14
10/10/2011	gjo	Migrate assignment from (S)-3-O-geranylgeranylglyceryl phosphate synthase to Geranylgeranylglyceryl phosphate synthase-like protein YerE
10/11/2011	gjo	Set master function to Geranylgeranylglyceryl phosphate synthase-like protein YerE
1/20/2012	md5_consistency	Set master function to (S)-3-O-geranylgeranylglyceryl phosphate synthase
1/20/2012	md5_consistency	assignment made to reconcile multiple functions for the same md5
5/13/2013	RossO	Set master function to Geranylgeranylglyceryl phosphate synthase-like protein YerE
5/13/2013	RossO	Assignment projected from fig|1155134.3.peg.2195 based on solid rectangle
1/21/2015	annotation_transfer	Migrating 2 annotations for fig|158878.1.peg.1906 from core seed (including function assignment) at 2015-01-22 01:15:09
1/21/2015	gjo	Migrate assignment from Geranylgeranylglyceryl phosphate synthase-like protein YerE to Heptaprenylglyceryl phosphate synthase (EC 2.5.1.n9)
1/21/2015	gjo	Assignment projected from fig|279808.3.peg.1759 based on solid rectangle
1/22/2015	gjo	Set master function to Heptaprenylglyceryl phosphate synthase (EC 2.5.1.n9)

We have assigned the function "Heptaprenylglyceryl phosphate synthase (EC 2.5.1.n9)" to the encoded protein. The protein occurs in 1 subsystem: "Archaeal lipids". In "Archaeal lipids", it appears to play a functional role that we have not associated with any other gene. The function of this gene is asserted in 24684232 and 21761520. The function of genes having the same functional roles have been described in Bacillus subtilis (9701819), Methanothermobacter thermautotrophicus (11732904) and Thermoplasma acidophilum (12801917). These are homologous proteins which implement the same function.

The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.