Subsystem: YjeE

This subsystem's description is:

For more information, please check out the description and the additional notes tabs, below

DiagramFunctional RolesSubsystem SpreadsheetAdditional Notes 

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Group Alias
Abbrev.Functional RoleReactionsScenario ReactionsGOLiterature
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Taxonomy Pattern 
Organism 
Domain
Variant [?] 
active
YjeECOG3178CBSYjeF-NYjeF-CYeaZ
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Variant codes:
+1 - YjeE is present
+2 - YjeF is present
+4 - YeaZ is present

ATPase YjeE, predicted to have essential role in cell wall biosynthesis

A protein of unkown function.
Present in nearly all Bacteria, but not in Archae or Eucarya
Present in many members of Mycoplasmales and Anaplasma; perhaps we should rethink the cell wall biosynthesis designation.
It is essentical in E. coli.
Includes a Walker A box and B box.
Binds ADP at about 8 micromolar
Residues involved in ADP/ATP binding are essential.
Very poor ATPase (1 per hour)


COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases
fused with YjeE in some alpha Proteobacteria (but never clustered elsewhere!)


YjeF protein
Function unknown.
Often called sugar phosphatase.
Often clustered with YjeE, but also present in most Archaea
Often present in a truncated (C-terminal 1/2) form.

Inactive homolog of metal-dependent proteases, putative molecular chaperone
YeaZ
Often clusterer with YjeE and/or YjeF

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LITERATURE