Subsystem: Translation initiation factors eukaryotic and archaeal

This subsystem's description is:

For more information, please check out the description and the additional notes tabs, below

DiagramFunctional RolesSubsystem SpreadsheetAdditional Notes 

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Group Alias
Abbrev.Functional RoleReactionsScenario ReactionsGOLiterature
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Taxonomy Pattern 
Organism 
Domain
Variant [?] 
active
eIF-2aeIF-2beIF-2geIF-5AeIF-6eIF-1AIF-2eIF-2BaeIF-2BabdSUI1-r
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Variant codes:
1 Basal archaeal
2 Archaea with eIF-2Babd
3 Mixture of eukaryotic types
4 Encephalitozoon cuniculi type, highly reduced eukaryotic (nearly arhcaeal, but some eukaryote-specific factors)


Translation initiation factor SUI1 (= eIF-1) (Eucarya)
Translation initiation factor SUI1-related protein (Archaea and Bacteria)

Translation initiation factor 1A

Translation initiation factor 2 (all Domains; = eIF-5B)

Eukaryotic translation initiation factor 2 alpha subunit
Eukaryotic translation initiation factor 2 beta subunit
Eukaryotic translation initiation factor 2 gamma subunit

Translation initiation factor 2B alpha subunit
Translation initiation factor 2B beta subunit
Translation initiation factor 2B gamma subunit
Translation initiation factor 2B delta subunit
Translation initiation factor 2B epsilon subunit
Translation initiation factor 2B alpha/beta/delta-type subunit (Archaea)
Translation initiation factor 2B subunit-related protein

Eukaryotic translation initiation factor 3 135 kDa subunit
Eukaryotic translation initiation factor 3 110 kDa subunit
Eukaryotic translation initiation factor 3 93 KDa subunit
Eukaryotic translation initiation factor 3 90 KDa subunit
Eukaryotic translation initiation factor 3 39 KDa subunit
Eukaryotic translation initiation factor 3 30 KDa subunit
Eukaryotic translation initiation factor 3 RNA-binding subunit

Eukaryotic translation initiation factor 4A
watch out for "SSU rRNA-processing ATP-dependent RNA helicase FAL1"
and "DEAD box RNA helicase interacting with mRNA decapping and deadenylase complexes"

Eukaryotic translation initiation factor 4B

Eukaryotic translation initiation factor 4E

Eukaryotic translation initiation factor 4H (Metazoa)

Eukaryotic translation initiation factor 5

Translation elongation factor P; Eukaryotic translation initiation factor 5A

Eukaryotic translation initiation factor 6

More specific notes:

eIF-2Babd is not present in Ferroplasma DNA sequence, even though other Thermoplasmales have it

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Some candidates that are not included:

Translation initiation factor IF-2, mitochondrial precursor
Translation initiation factor eIF-4E associated protein