Subsystem: Staphylococcus Two-component and Pore-forming Cytolysins

This subsystem's description is:

Staphylococcal gamma-hemolysin (Hlg), leukocidin (Luk), and Panton-Valentine leukocidin (PVL) are two-component and hetero-oligomeric pore-forming cytolytic toxins (or cytolysin)

For more information, please check out the description and the additional notes tabs, below

Literature ReferencesAssembly of Staphylococcus aureus gamma-hemolysin into a pore-forming ring-shaped complex on the surface of human erythrocytes. Sugawara N FEBS letters 1997 Jun 309237657
DiagramFunctional RolesSubsystem SpreadsheetDescriptionAdditional Notes 

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Group Alias
Abbrev.Functional RoleReactionsScenario ReactionsGOLiterature
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Taxonomy Pattern 
Organism 
Domain
Variant [?] 
active
HlgAHlgBHlgCSBILukDLukELuk-PVLukS-PVHla
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Staphylococcal gamma-hemolysin (Hlg), leukocidin (Luk), and Panton-Valentine leukocidin (PVL) are two-component and hetero-oligomeric pore-forming cytolytic toxins (or cytolysin)
Included in this SS is a gene encoding the IgG-binding protein SBI, always co-occurring with the hlg gene cluster. I have also included Alpha-haemolysin, just to give it a home.