Subsystem: Recycling of Peptidoglycan Amino Acids

This subsystem's description is:

Bacteria break down and reuse over 60% of the peptidoglycan (PG)of their side wall each generation; recycling of newly made peptidoglycan during septum synthesis occurs at an even faster rate. Gram-negative bacteria living in the colon tend to have a complete repertoire of enzymes for recycling, whereas other organisms have a more limited arsenal.
PG degradation products released into the periplasm by endopeptidases, transglycosidases and amidases are available for uptake by AmpG permease and can enter the recycling pathway (right side of the accompanying Illustration). Recycling is not essential under laboratory conditions.

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Literature ReferencesHow bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan). Park JT Microbiology and molecular biology reviews : MMBR 2008 Jun18535144
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