Subsystem: Lysine biosynthesis AAA pathway 2

This subsystem's description is:

For more information, please check out the description and the additional notes tabs, below

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Group Alias
Abbrev.Functional RoleReactionsScenario ReactionsGOLiterature
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Taxonomy Pattern 
Organism 
Domain
Variant [?] 
active
LysZAAAT*HACHCSHICDHLysXLysYLysJLysK
This SS was started by BenjaminS_UFL.

Notes copied from Lysine_biosynthesis_AAA_pathway:
Variant codes:
1= Complete pathway as in Thermus thermophilus
-1= Pathway not found, checked
0= Pathway still under inspection
2= Pathway possible, requires more investigation


Yeast:
LYS2: L-aminoadipate-semialdehyde dehydrogenase large subunit (EC 1.2.1.31)
A key step in fungal biosynthesis of lysine, enzymatic reduction of alpha-aminoadipate at C6 to the semialdehyde is catalyzed by holo-Lys2p, which is generated from apo-Lys2p by addition of phosphopantetheine by Lys5p

LYS5: L-aminoadipate-semialdehyde dehydrogenase small subunit (EC 1.2.1.31)
Converts inactive apo-form of Lys2p (alpha-aminoadipate semialdehyde reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine. (Has been called small subunit of alpha-aminoadipate reductase.)

LYS 9: Saccharopine dehydrogenase [NADP , L-glutamate-forming] (EC 1.5.1.10)
Seventh step in lysine biosynthesis pathway

Currently selected organism: Sulfolobus acidocaldarius DSM 639 (open scenarios overview page for organism)



ScenarioInput CompoundsOutput CompoundsPaint on MapStatus in 330779.3



Lysine biosynthesis (link to KEGG)