Subsystem: Lysine degradation
This subsystem's description is:
At least 9 pathways exist for the degradation of lysine in mammals, plants, bacteria and fungi. The initial products of lysine degradation in these pathways include: L-saccharopine in mammals and plants; beta-L-lysine, 5-aminovaleramide, N6-hydroxylysine, cadaverine, and alpha-aminoadipate-delta-semialdehyde in bacteria; and alpha -aminoadipate-delta-semialdehyde, D-lysine, N6-acetyl-L-lysine, and 6-amino-2-oxocaproic acid in yeasts and fungi.
====Variant codes:==========
1.0 - Cadaverine pathway (from L-lysine to {delta}-aminovalerate via cadaverine/1-piperidine);
2.0 - AMV (aminovalerate) pathway (from L-lysine to glutaric acid);
3.0 - AMA (aminoadipate ) pathway (from D-lysine to 2-aminoadipate);
4.0 - AMV + AMA (as in Pseudomonas putida );
4.1 - AMV + AMA + Cadaverine pathway(as in Pseudomonas aeruginosa );
5.0 - Lysine fermentation ( as in Fusobacterium nucleatum);
6.0 - Eukaryotic pathway ( as in Saccharomyces cerevisiae).
For more information, please check out the description and the additional notes tabs, below
| Diagram | Functional Roles | Subsystem Spreadsheet | Description | Additional Notes | Scenarios | |||||||||
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