Subsystem: LOS core oligosaccharide biosynthesis
This subsystem's description is:
In E. coli, Salmonella, and K. pneumoniae the core oligosaccharide biosynthesis genes are clustered on the chromosome. These loci generally encode all of the activities required for outer-core assembly as well as the transferases needed for inner-core synthesis. In E. coli and Salmonella, the waa locus consists of three operons. The operons are defined by the first gene in each transcriptional unit: gmhD-, waaQ-, and waaA.
1.0 – complete set of genes required for biosynthesis and transfer of L,D-heptose (Heptose biosynthesis pathway);
1.x – some genes are missing in the Heptose biosynthesis pathway;
2.0 - whole set of Heptose biosynthesis and the Outer core (LOS core) biosynthesis genes;
2.x - some genes are missing in LOS core oligosaccharide biosynthesis.
For more information, please check out the description and the additional notes tabs, below
|Literature References||Lipopolysaccharide endotoxins. Raetz CR Annual review of biochemistry 2002||12045108||The Campylobacter jejuni glycome. Karlyshev AV FEMS microbiology reviews 2005 Apr||15808749|
|Diagram||Functional Roles||Subsystem Spreadsheet||Description||Additional Notes||Scenarios|