Subsystem: Glycine and Serine Utilization

This subsystem's description is:

Glycin and Serine are nonessential amino acids. In plants and bacteria Serine can be directly converted into cysteine (Cysteine formation route). Glycine catabolism proceed mainly by interconversion with Serine and requires the participation of tetrahydrofolate (THF) C1-transfer system. The major route for serine catabolism is the serine dehydratase reaction, leading to pyruvate (Pyruvate route). Another way of serine utilization is reconversion of it to 3-phosphoglycerate (Glycerate route).

========Variant codes:==============

1.1 - Glycine_cleavage_system
1.2 - Pyruvate_route
1.3 - Glycerate_route
1.4 - Cysteine_formation

1.12 - Glycine_cleavage_system + Pyruvate_route
1.123 - Glycine_cleavage_system + Pyruvate_route + Glycerate_route
1.1234 - Glycine_cleavage_system + Pyruvate_route + Glycerate_route + Cysteine_formation

For more information, please check out the description and the additional notes tabs, below

Literature ReferencesL-serine catabolism via an oxygen-labile L-serine dehydratase is essential for colonization of the avian gut by Campylobacter jejuni. Velayudhan J Infection and immunity 2004 Jan14688104
DiagramFunctional RolesSubsystem SpreadsheetDescriptionAdditional Notes 

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Group Alias
Abbrev.Functional RoleReactionsScenario ReactionsGOLiterature

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