Subsystem: Glycerolipid and Glycerophospholipid Metabolism in Bacteria
This subsystem's description is:
Phospholipids are membrane components. In addition to providing the membrane matrix, phospholipids are also involved in synthesizing several types of surface molecules. The phosphoethanolamine head groups of phosphatidylethanolamine are transferred and attached to the lipopolysaccharide (LPS) core sugars and to periplasmic membrane-derived oligosaccharides (MDO). The head group of phosphatidylglycerol is used for modifying various lipoproteins and MDO. The entire molecule is used in the synthesis of cardiolipin.
The major phospholipids of E. coli are phosphatidylethanolamine (PE), phosphatidylglycerol(PG) and cardiolipin. All phospholipids contain sn-glycerol-3-phosphate esterified with fatty acids at the sn-1 and sn-2 positions.
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|Literature References||[Therapy of caries profunda]. Oehler V Stomatologie der DDR 1981 May||6949372||Thematic review series: Glycerolipids. Acyltransferases in bacterial glycerophospholipid synthesis. Zhang YM Journal of lipid research 2008 Sep||18369234||Biosynthesis and function of phospholipids in Escherichia coli. Raetz CR The Journal of biological chemistry 1990 Jan 25||2404013||High alveolar surface tension increases clearance of technetium 99m diethylenetriamine-pentaacetic acid. Nieman G The Journal of thoracic and cardiovascular surgery 1990 Jul||1694937||Coupling of fatty acid and phospholipid synthesis in Bacillus subtilis. Paoletti L Journal of bacteriology 2007 Aug||17557823||Phosphatidic acid, a key intermediate in lipid metabolism. Athenstaedt K European journal of biochemistry 1999 Nov||10542045|
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