Subsystem: Exopolysaccharide Biosynthesis

This subsystem's description is:

For more information, please check out the description and the additional notes tabs, below

DiagramFunctional RolesSubsystem SpreadsheetAdditional Notes 

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Group Alias
Abbrev.Functional RoleReactionsScenario ReactionsGOLiterature

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This is an experimental (temporary) subsystem just to protect the Esp genes cluster until the more specific subsystem will be encoded and developed (Cellulose SS, for example).


1. J. R. Broadbent, D. J. McMahon, D. L. Welker, C. J. Oberg, and S. Moineau. Biochemistry, Genetics, and Applications of Exopolysaccharide Production in Streptococcus thermophilus: A Review. J Dairy Sci, February 1, 2003; 86(2): 407 - 423. PMID: 12647947.

2. N. Dabour and G. LaPointe. Identification and Molecular Characterization of the Chromosomal Exopolysaccharide Biosynthesis Gene Cluster from Lactococcus lactis subsp. cremoris SMQ-461. Appl. Envir. Microbiol., November 1, 2005; 71(11): 7414 - 7425.

3. Almiron-Roig E, Mulholland F, Gasson MJ, Griffin AM (2000) The complete cps gene cluster from Streptococcus thermophilus NCFB 2393 involved in the biosynthesis of a new exopolysaccharide. Microbiology 146:2793-2802. PMID: 11065358

4. Stingele F, Newell JW, Neeser JR. Unraveling the function of glycosyltransferases in Streptococcus thermophilus Sfi6.J Bacteriol. 1999 Oct;181(20):6354-60.PMID: 10515925

5. Lamothe GT, Jolly L, Mollet B, Stingele F. Genetic and biochemical characterization of exopolysaccharide biosynthesis by Lactobacillus delbrueckii subsp. bulgaricus. Arch Microbiol. 2002 Sep;178(3):218-28. Epub 2002 Jun 20. PMID: 12189423

6. Bentley SD, Aanensen DM, Mavroidi A, Saunders D, Rabbinowitsch E, Collins M, Donohoe K, Harris D, Murphy L, Quail MA, Samuel G, Skovsted IC, Kaltoft MS, Barrell B, Reeves PR, Parkhill J, Spratt BG. Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes.
PLoS Genet. 2006 Mar;2(3):e31. PMID: 16532061