Subsystem: CytR regulation
This subsystem's description is:
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Literature References | Dual-function regulators: the cAMP receptor protein and the CytR regulator can act either to repress or to activate transcription depending on the context. Rasmussen PB Proceedings of the National Academy of Sciences of the United States of America 1996 Sep 17 | 8816767 |
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Diagram | Functional Roles | Subsystem Spreadsheet | Additional Notes | |||||||||
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CytR is a global transcription regulator of pyrimidine nucleotide metabolism in many gamma Proteobacteria. It functions in association with Cyclic AMP receptor protein (Crp). Usually viewed as a repressor, it can also be an activator. For example, see: Rasmussen, P. B., Holst, B., and Valentin-Hansen, P. 1996. Dual-function regulators: the cAMP receptor protein and the CytR regulator can act either to repress or to activate transcription depending on the context. Proc. Natl. Acad. Sci. USA. 93:10151-10155. KEGG and UniProt call this protein "regulator for deo operon, udp, cdd, tsx, nupC, and nupG". CytR is similar to many transcriptonal regulators, and the circumscription is uncertain. Variant codes: -1 - not identified 1 - identified############################### LITERATURE |
