Subsystem: Capsular heptose biosynthesis

This subsystem's description is:

Capsular polysaccharides (CPSs) are found on the surface of a large number of bacterial species. CPSs are known to play an important role in bacterial survival and persistence in the environment and often contribute to pathogenesis. In addition, through structural variation, the potential to mimic host cell antigens, and the ability to resist innate mechanisms such as phagocytosis and complement-mediated killing, bacterial CPSs play a role in evasion of host immune responses.

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Literature ReferencesAnalysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses. Karlyshev AV Molecular microbiology 2005 Jan15612919
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