Subsystem: Acyl-CoA thioesterase II

This subsystem's description is:

Acyl-CoA thioesterase II is an Acyl-CoA thioesterase that is very different from Acyl-CoA thioesterase in both sequence and structure. Its precise role is not fully known, but it seems specific for short to medium length 3-hyroxy acyl chains (perhaps 3-hydroxybutyric acid to 3-hydroxydecanoic acid). It has been proposed that it is present to purify the pool of acyl-CoA.

Mycobacteria and relatives seem to have a large number quite similar paralogs.

It has a few distant paralogs, which might be associated with the synthesis of particular compounds.

For more information, please check out the description and the additional notes tabs, below

DiagramFunctional RolesSubsystem SpreadsheetDescription 

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Acyl-CoA thioesterase II is an Acyl-CoA thioesterase that is very different from Acyl-CoA thioesterase in both sequence and structure. Its precise role is not fully known, but it seems specific for short to medium length 3-hyroxy acyl chains (perhaps 3-hydroxybutyric acid to 3-hydroxydecanoic acid). It has been proposed that it is present to purify the pool of acyl-CoA.

Mycobacteria and relatives seem to have a large number quite similar paralogs.

It has a few distant paralogs, which might be associated with the synthesis of particular compounds.