│││││││││││││││││││││││││││││││││││││││││││┌─

fig|502800.6.peg.1851         ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia pseudotuberculosis YPIII]

││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|502800.3.peg.1690         ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia pseudotuberculosis YPIII]

│││││││││││││││││││││││││││││││││││││││││┌┴┬─

fig|349747.3.peg.931         ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia pseudotuberculosis IP 31758]

││││││││││││││││││││││││││││││││││││││││┌┤│└─

fig|349747.9.peg.1958  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia pseudotuberculosis IP 31758]

│││││││││││││││││││││││││││││││││││││││││└┬─

fig|349746.9.peg.3378  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia pestis Angola]

│││││││││││││││││││││││││││││││││││││││┌┤│└─

fig|404217.5.peg.3519  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia pestis biovar Orientalis str. MG05-1020]

││││││││││││││││││││││││││││││││││││││││└┬─

fig|349965.3.peg.72  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia intermedia ATCC 29909]

││││││││││││││││││││││││││││││││││││││┌┤│└─

fig|527002.3.peg.1640         ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia aldovae ATCC 35236]

││││││││││││││││││││││││││││││││││││││││┌─

fig|349966.5.peg.2586  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia frederiksenii ATCC 33641]

│││││││││││││││││││││││││││││││││││││││└┤│┌─

fig|630.2.peg.1679         ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia enterocolitica 8081]

││││││││││││││││││││││││││││││││││││││││└┬┴─

fig|393305.7.peg.1860  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia enterocolitica subsp. enterocolitica 8081]

│││││││││││││││││││││││││││││││││││││┌┤││└┬─

fig|527012.3.peg.1249         ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia kristensenii ATCC 33638]

││││││││││││││││││││││││││││││││││││││││││└┬─

fig|527004.3.peg.341         ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia rohdei ATCC 43380]

│││││││││││││││││││││││││││││││││││││││││││└┬─

fig|349968.3.peg.3619  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia bercovieri ATCC 43970]

││││││││││││││││││││││││││││││││││││┌┤││││││└─

fig|349967.3.peg.55  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia mollaretii ATCC 43969]

││││││││││││││││││││││││││││││││││││││└─

fig|527005.3.peg.1118         ⌘ NAD-dependent protein deacetylase of SIR2 family [Yersinia ruckeri ATCC 29473]

│││││││││││││││││││││││││││││││││││││││┌─

fig|615.1.peg.148  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Serratia marcescens Db11]

│││││││││││││││││││││││││││││││││││┌┤└┬┴─

fig|667129.3.peg.3317         ⌘ NAD-dependent protein deacetylase of SIR2 family [Serratia odorifera DSM 4582]

││││││││││││││││││││││││││││││││││││││└┬─

fig|399741.3.peg.2012  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Serratia proteamaculans 568]

│││││││││││││││││││││││││││││││││││││││└─

fig|1206776.4.peg.2104  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Serratia plymuthica A30]

││││││││││││││││││││││││││││││││││││└───

fig|343509.12.peg.2460  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Sodalis glossinidius str. 'morsitans']

││││││││││││││││││││││││││││││││││┌┤│││┌─

fig|1223571.3.peg.1643         ⌘ NAD-dependent protein deacetylase of SIR2 family [Dickeya chrysanthemi NCPPB 516]

││││││││││││││││││││││││││││││││││││││┌┴─

fig|1223571.3.peg.8468  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Dickeya chrysanthemi NCPPB 516]

│││││││││││││││││││││││││││││││││││││┌┴─

fig|590409.4.peg.1620         ⌘ NAD-dependent protein deacetylase of SIR2 family [Dickeya dadantii Ech586]

│││││││││││││││││││││││││││││││││││└┬┴─

fig|579405.3.peg.1731         ⌘ NAD-dependent protein deacetylase of SIR2 family [Dickeya dadantii Ech703]

││││││││││││││││││││││││││││││││││││└┬─

fig|561230.3.peg.2490         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pectobacterium carotovorum subsp. carotovorum PC1]

│││││││││││││││││││││││││││││││││││││└┬─

fig|558270.3.peg.1324         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pectobacterium carotovorum subsp. carotovorum WPP14]

││││││││││││││││││││││││││││││││││││││└┬─

fig|561231.5.peg.2699         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pectobacterium wasabiae WPP163]

│││││││││││││││││││││││││││││││││┌┤││││└┬─

fig|218491.5.peg.1856         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pectobacterium atrosepticum SCRI1043]

││││││││││││││││││││││││││││││││││││││││└─

fig|1289594.3.peg.3154  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pectobacterium atrosepticum CFBP 6276]

│││││││││││││││││││││││││││││││││││││┌─

fig|498217.4.peg.1898  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Edwardsiella tarda EIB202]

││││││││││││││││││││││││││││││││││││┌┴─

fig|1027360.4.peg.3302  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Edwardsiella ictaluri ATCC 33202]

│││││││││││││││││││││││││││││││││││┌┴─

fig|667121.5.peg.127  ✚        NAD-dependent protein deacetylase of SIR2 family [Edwardsiella tarda ATCC 15947]

│││││││││││││││││││││││││││││││││││││││┌─

fig|291112.3.peg.1909         ⌘ NAD-dependent protein deacetylase of SIR2 family [Photorhabdus asymbiotica]

││││││││││││││││││││││││││││││││││└┤││┌┴─

fig|171440.1.peg.1170         ⌘ NAD-dependent protein deacetylase of SIR2 family [Photorhabdus asymbiotica subsp. asymbiotica]

│││││││││││││││││││││││││││││││││││││┌┴─

fig|243265.5.peg.3195  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Photorhabdus luminescens subsp. laumondii TTO1]

││││││││││││││││││││││││││││││││││││┌┴─

fig|406818.4.peg.2554         ⌘ NAD-dependent protein deacetylase of SIR2 family [Xenorhabdus bovienii SS-2004]

│││││││││││││││││││││││││││││││││││└┤│┌─

fig|1279010.3.peg.1287  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Proteus mirabilis PR03]

││││││││││││││││││││││││││││││││││││└┬┴─

fig|471881.3.peg.4152         ⌘ NAD-dependent protein deacetylase of SIR2 family [Proteus penneri ATCC 35198]

│││││││││││││││││││││││││││││││││││││└─┬─

fig|1157951.4.peg.305  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Providencia stuartii MRSN 2154]

│││││││││││││││││││││││││││││││││││││││└┬─

fig|521000.6.peg.2117         ⌘ NAD-dependent protein deacetylase of SIR2 family [Providencia rettgeri DSM 1131]

││││││││││││││││││││││││││││││││┌┤││││││└┬─

fig|1141661.3.peg.686  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Providencia alcalifaciens Dmel2]

│││││││││││││││││││││││││││││││││││││││││└┬─

fig|500637.6.peg.5706         ⌘ NAD-dependent protein deacetylase of SIR2 family [Providencia rustigianii DSM 4541]

││││││││││││││││││││││││││││││││││││││││││└─

fig|500637.6.peg.1842         ⌘ NAD-dependent protein deacetylase of SIR2 family [Providencia rustigianii DSM 4541]

││││││││││││││││││││││││││││││││││││││┌─

fig|644651.3.peg.2066         ⌘ NAD-dependent protein deacetylase of SIR2 family [Erwinia pyrifoliae DSM 12163]

│││││││││││││││││││││││││││││││││││││┌┴─

fig|716540.3.peg.1483  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Erwinia amylovora ATCC 49946]

│││││││││││││││││││││││││││││││││││┌─┴─

fig|465817.9.peg.2052         ⌘ NAD-dependent protein deacetylase of SIR2 family [Erwinia tasmaniensis Et1/99]

││││││││││││││││││││││││││││││││││┌┴┬─

fig|592316.4.peg.1508  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pantoea sp. At-9b]

││││││││││││││││││││││││││││││││││││└─

fig|706191.3.peg.1554         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pantoea ananatis LMG 20103]

│││││││││││││││││││││││││││││││││││││││┌─

fig|272620.3.peg.1134         ⌘ NAD-dependent protein deacetylase of SIR2 family [Klebsiella pneumoniae MGH 78578]

││││││││││││││││││││││││││││││││││││││┌┼─

fig|272620.9.peg.1146         ⌘ NAD-dependent protein deacetylase of SIR2 family [Klebsiella pneumoniae subsp. pneumoniae MGH 78578]

│││││││││││││││││││││││││││││││││││││┌┤└─

fig|640131.3.peg.3212  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Klebsiella variicola At-22]

││││││││││││││││││││││││││││││││││││││└┬─

fig|667127.3.peg.100         ⌘ NAD-dependent protein deacetylase of SIR2 family [Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884]

│││││││││││││││││││││││││││││││││└┤│┌┤│└─

fig|1316939.3.peg.1752  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Klebsiella pneumoniae G5-2]

│││││││││││││││││││││││││││││││││││││└┬─

fig|399742.4.peg.1614         ⌘ NAD-dependent protein deacetylase of SIR2 family [Enterobacter sp. 638]

│││││││││││││││││││││││││││││││││││┌┤│└─

fig|399742.10.peg.1776         ⌘ NAD-dependent protein deacetylase of SIR2 family [Enterobacter sp. 638]

││││││││││││││││││││││││││││││││││││└┬─

fig|500639.8.peg.943         ⌘ NAD-dependent protein deacetylase of SIR2 family [Enterobacter cancerogenus ATCC 35316]

│││││││││││││││││││││││││││││││││││││└─

fig|716541.4.peg.2691         ⌘ NAD-dependent protein deacetylase of SIR2 family [Enterobacter cloacae subsp. cloacae ATCC 13047]

│││││││││││││││││││││││││││││││││││││┌─

fig|290339.8.peg.1986  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Cronobacter sakazakii ATCC BAA-894]

││││││││││││││││││││││││││││││││││└┤┌┴─

fig|413502.6.peg.1613  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Cronobacter turicensis]

│││││││││││││││││││││││││││││││││││││││┌─

fig|742730.3.peg.3254  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Citrobacter freundii 4_7_47CFAA]

││││││││││││││││││││││││││││││││││││││┌┴─

fig|500640.5.peg.1203         ⌘ NAD-dependent protein deacetylase of SIR2 family [Citrobacter youngae ATCC 29220]

│││││││││││││││││││││││││││││││││││││┌┴┬─

fig|290338.6.peg.1618  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Citrobacter koseri ATCC BAA-895]

│││││││││││││││││││││││││││││││││││└┤││└─

fig|637910.3.peg.1164         ⌘ NAD-dependent protein deacetylase of SIR2 family [Citrobacter rodentium ICC168]

│││││││││││││││││││││││││││││││││││││││││││┌─

fig|1182167.3.peg.405  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN00325]

││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|209261.1.peg.1590  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella enterica subsp. enterica serovar Typhi Ty2]

││││││││││││││││││││││││││││││┌─┤││││││││┌┴─

fig|936157.3.peg.2084  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella enterica subsp. enterica serovar Weltevreden str. 2007-60-3289-1]

││││││││││││││││││││││││││││││││││││└┤││┌┴┬─

fig|321314.9.peg.1539  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella enterica subsp. enterica serovar Choleraesuis str.]

│││││││││││││││││││││││││││││││││││││││┌┤│└─

fig|476213.4.peg.2597         ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella enterica subsp. enterica serovar Paratyphi C strain]

││││││││││││││││││││││││││││││││││││││││└┬─

fig|272994.6.peg.1862  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7]

││││││││││││││││││││││││││││││││││││││┌┤│└┬─

fig|295319.3.peg.910         ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella enterica subsp. enterica serovar Paratypi A str. ATCC 9150]

││││││││││││││││││││││││││││││││││││││││││└─

fig|1072572.3.peg.1688  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella enterica subsp. enterica serovar Paratyphi A str. ZJ98-53]

│││││││││││││││││││││││││││││││││││││└┤└┬─

fig|12149.1.peg.1180  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella bongori 12149]

││││││││││││││││││││││││││││││││││││││││└─

fig|41514.7.peg.1690  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salmonella enterica subsp. arizonae serovar 62:z4,z23:--]

│││││││││││││││││││││││││││││││││││││││┌─

fig|502347.3.peg.2041         ⌘ NAD-dependent protein deacetylase of SIR2 family [Escherichia albertii TW07627]

││││││││││││││││││││││││││││││││││││││└┤│┌─

fig|1005563.3.peg.1344  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Escherichia coli ARS4.2123]

││││││││││││││││││││││││││││││││││││││││┌┴─

fig|405955.9.peg.946         ⌘ NAD-dependent protein deacetylase of SIR2 family [Escherichia coli APEC O1]

│││││││││││││││││││││││││││││││││││││││└┤│┌─

fig|216592.1.peg.1544  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Escherichia coli 042]

│││││││││││││││││││││││││││││││││││││││││┌┴─

fig|869677.4.peg.1164  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Escherichia coli 96.0497]

││││││││││││││││││││││││││││││││││││││││└┤│┌─

fig|766161.3.peg.1386  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shigella flexneri 6603-63]

││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|585054.5.peg.1237  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Escherichia fergusonii ATCC 35469]

│││││││││││││││││││││││││││││││││││││││││└┤│┌─

fig|344609.3.peg.4578  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shigella boydii BS512]

│││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|754093.3.peg.5065  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shigella dysenteriae 1617]

││││││││││││││││││││││││││││││││││││││││││└┤┌─

fig|1169355.3.peg.2458  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Escherichia coli KTE38]

│││││││││││││││││││││││││││││││││││││││││││└┼─

fig|1182731.3.peg.1885  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Escherichia coli KTE158]

││││││││││││││││││││││││││││││││││││││││││││└─

fig|1116087.3.peg.1293  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Escherichia coli P0305260.13]

││││││││││││││││││││││││││││││││││││┌─

fig|1076135.3.peg.2343  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Aeromonas salmonicida subsp. salmonicida 01-B526]

│││││││││││││││││││││││││││││││││┌──┴─

fig|380703.7.peg.2318  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Aeromonas hydrophila subsp. hydrophila ATCC 7966]

│││││││││││││││││││││││││││││││││││││┌─

fig|314292.13.peg.2253  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio angustum S14]

││││││││││││││││││││││││││││││││││││┌┴─

fig|121723.5.peg.1652         ⌘ NAD-dependent protein deacetylase of SIR2 family [Photobacterium sp. SKA34]

││││││││││││││││││││││││││││││││└┤│┌┴──

fig|675817.3.peg.1123         ⌘ NAD-dependent protein deacetylase of SIR2 family [Photobacterium damselae subsp. damselae CIP 102761]

││││││││││││││││││││││││││││││││││┌┴─┬─

fig|314280.5.peg.2736  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Photobacterium profundum 3TCK]

│││││││││││││││││││││││││││││││││││││└─

fig|298386.1.peg.4122  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Photobacterium profundum SS9]

│││││││││││││││││││││││││││││││││││┌──

fig|675812.3.peg.2717         ⌘ NAD-dependent protein deacetylase of SIR2 family [Grimontia hollisae CIP 101886]

│││││││││││││││││││││││││││││││││└┤││││┌─

fig|312309.11.peg.1328  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio fischeri ES114]

││││││││││││││││││││││││││││││││││││││┌┴─

fig|388396.7.peg.2352  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio fischeri MJ11]

││││││││││││││││││││││││││││││││││││┌─┴─

fig|316275.9.peg.1658  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Aliivibrio salmonicida LFI1238]

││││││││││││││││││││││││││││││││││└┤││││┌─

fig|1191324.3.peg.2054  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio tasmaniensis 1F-267]

│││││││││││││││││││││││││││││┌┤││││││││┌┴─

fig|1191309.3.peg.3087  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio splendidus FF-500]

││││││││││││││││││││││││││││││││││││││┌┴─

fig|575788.5.peg.2778  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio splendidus LGP32]

│││││││││││││││││││││││││││││││││││││┌┴─

fig|391574.12.peg.1468         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrionales bacterium SWAT-3]

│││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|417398.15.peg.1538  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio cholerae MZO-2]

│││││││││││││││││││││││││││││││││││└┤│││││││││┌┴─

fig|345074.15.peg.2329         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio cholerae RC385]

│││││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|592313.3.peg.2572         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio cholerae 12129(1)]

││││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|991950.4.peg.2453  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio cholerae HC-06A1]

│││││││││││││││││││││││││││││││││││││││││││┌┴┬─

fig|992002.3.peg.1986  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio cholerae HC-44C1]

││││││││││││││││││││││││││││││││││││││││││┌┤│└─

fig|412966.3.peg.1785  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio cholerae 1587]

│││││││││││││││││││││││││││││││││││││││││┌┤└─

fig|675810.3.peg.1947         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio sp. RC341]

││││││││││││││││││││││││││││││││││││└┤││┌┤└─

fig|675815.3.peg.731         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio sp. RC586]

│││││││││││││││││││││││││││││││││││││││││└┬─

fig|675820.3.peg.2712         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio mimicus VM223]

│││││││││││││││││││││││││││││││││││││││┌┤│└┬─

fig|671074.4.peg.1326  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio mimicus VM603]

│││││││││││││││││││││││││││││││││││││││││││└─

fig|675806.3.peg.1177         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio mimicus MB-451]

││││││││││││││││││││││││││││││││││││││┌┤└─

fig|903510.3.peg.1823  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio furnissii NCTC 11218]

│││││││││││││││││││││││││││││││││││││││└──

fig|675813.3.peg.1411         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio metschnikovii CIP 69.14]

││││││││││││││││││││││││││││││││││││││││││┌─

fig|391586.4.peg.3617         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio parahaemolyticus 16]

│││││││││││││││││││││││││││││││││││││││││┌┴─

fig|675814.3.peg.4150         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio coralliilyticus ATCC BAA-450]

│││││││││││││││││││││││││││││││││││││└┤│┌┴─

fig|675816.3.peg.3048  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio orientalis CIP 102891]

││││││││││││││││││││││││││││┌┤│││││││││┌┴┬─

fig|216895.17.peg.2573  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio vulnificus CMCP6]

│││││││││││││││││││││││││││││││││││││││││└─

fig|1229202.3.peg.3120  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio vulnificus B2]

││││││││││││││││││││││││││││││││││││││││││┌─

fig|1234592.3.peg.2580  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio sp. 712i1]

││││││││││││││││││││││││││││││││││││││└┤│┌┴─

fig|674977.3.peg.4549         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio alginolyticus 40B]

││││││││││││││││││││││││││││││││││││││││┌┴─

fig|150340.3.peg.2489  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio sp. Ex25]

│││││││││││││││││││││││││││││││││││││││││││┌─

fig|627611.3.peg.478  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio parahaemolyticus K5030]

│││││││││││││││││││││││││││││││││││││││└┤│┌┴─

fig|223926.1.peg.1524  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio parahaemolyticus RIMD 2210633]

│││││││││││││││││││││││││││││││││││││││││┌┴─

fig|419109.14.peg.71         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio parahaemolyticus AQ3810]

││││││││││││││││││││││││││││││││││││││││└┤│┌──

fig|391591.24.peg.4649         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio shilonii AK1]

│││││││││││││││││││││││││││││││││││││││││└┬┴─

fig|314289.8.peg.781         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio sp. AND4]

││││││││││││││││││││││││││││││││││││││││││└┬─

fig|673519.3.peg.4052         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio harveyi 1DA3]

│││││││││││││││││││││││││││┌┤││││││││││││││└┬─

fig|338187.4.peg.1681  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio harveyi ATCC BAA-1116]

││││││││││││││││││││││││││││││││││││││││││││└─

fig|410291.13.peg.1770         ⌘ NAD-dependent protein deacetylase of SIR2 family [Vibrio harveyi HY01]

││││││││││││││││││││││││││││││└┬───

fig|339671.5.peg.1349  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Actinobacillus succinogenes 130Z]

│││││││││││││││││││││││││││││││└┬───

fig|669261.3.peg.945         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mannheimia haemolytica serotype A2 str. OVINE]

││││││││││││││││││││││││││││││││└┬────

fig|637911.3.peg.1034         ⌘ NAD-dependent protein deacetylase of SIR2 family [Actinobacillus minor NM305]

│││││││││││││││││││││││││││││││││└─┬─

fig|272843.6.peg.1006  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pasteurella multocida subsp. multocida str. Pm70]

││││││││││││││││││││││││││┌┤│││││││└─

fig|667128.3.peg.1605         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pasteurella dagmatis ATCC 43325]

│││││││││││││││││││││││││││││└┬────

fig|207954.4.peg.3003         ⌘ NAD-dependent protein deacetylase of SIR2 family [Neptuniibacter caesariensis]

││││││││││││││││││││││││││││││└───┬─

fig|399739.6.peg.774         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas mendocina ymp]

││││││││││││││││││││││││││││││││││└─

fig|399739.8.peg.802         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas mendocina ymp]

││││││││││││││││││││││││││││└─┬───

fig|573065.5.peg.719  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Asticcacaulis excentricus CB 48]

│││││││││││││││││││││││││┌┤│││└────

fig|391600.3.peg.2614         ⌘ NAD-dependent protein deacetylase of SIR2 family [Brevundimonas sp. BAL3]

│││││││││││││││││││││││││││└┬─────

fig|391615.3.peg.471         ⌘ NAD-dependent protein deacetylase of SIR2 family [gamma proteobacterium HTCC5015]

││││││││││││││││││││││││││││└──┬─

fig|393595.15.peg.1146  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Alcanivorax borkumensis SK2]

│││││││││││││││││││││││││││││││└─

fig|236097.3.peg.1058         ⌘ NAD-dependent protein deacetylase of SIR2 family [Alcanivorax sp. DG881]

│││││││││││││││││││││││││││┌───────

fig|648757.3.peg.2369  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodomicrobium vannielii ATCC 17100]

││││││││││││││││││││││││││└┤┌───

fig|331869.3.peg.5885         ⌘ NAD-dependent protein deacetylase of SIR2 family [alpha proteobacterium BAL199]

││││││││││││││││││││││││┌┤│└┤││┌───

fig|431944.4.peg.1996         ⌘ NAD-dependent protein deacetylase of SIR2 family [Magnetospirillum gryphiswaldense MSR-1]

││││││││││││││││││││││││││││└┬─┴───

fig|342108.5.peg.811  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Magnetospirillum magneticum AMB-1]

│││││││││││││││││││││││││││││└┬─────

fig|137722.3.peg.99  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Azospirillum sp. B510]

││││││││││││││││││││││││││││││└┬───

fig|414684.5.peg.2811  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodospirillum centenum SW]

│││││││││││││││││││││││┌┤││││││└───

fig|1036743.4.peg.3743  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodospirillum rubrum F11]

│││││││││││││││││││││││││└──────

fig|525371.3.peg.1940         ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseomonas cervicalis ATCC 49957]

││││││││││││││││││││││││││┌───────

fig|314254.3.peg.2932  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Oceanicaulis alexandrii HTCC2633]

││││││││││││││││││││││││└─┤│││││┌─

fig|190650.1.peg.3454         ⌘ NAD-dependent protein deacetylase of SIR2 family [Caulobacter crescentus CB15]

││││││││││││││││││││││││││││┌───┴─

fig|190650.5.peg.3490  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Caulobacter crescentus CB15]

││││││││││││││││││││││││││└─┤│││││┌──

fig|460265.11.peg.6926         ⌘ NAD-dependent protein deacetylase of SIR2 family [Methylobacterium nodulans ORS 2060]

││││││││││││││││││││││││││││││││┌─┴──

fig|426117.3.peg.5167  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Methylobacterium sp. 4-46]

││││││││││││││││││││││││││││└──┬┴───

fig|426355.14.peg.4032         ⌘ NAD-dependent protein deacetylase of SIR2 family [Methylobacterium radiotolerans JCM 2831]

│││││││││││││││││││││││││││││││└─┬─

fig|441620.7.peg.2226         ⌘ NAD-dependent protein deacetylase of SIR2 family [Methylobacterium populi BJ001]

│││││││││││││││││││││││││││││││││└┬─

fig|661410.3.peg.2781         ⌘ NAD-dependent protein deacetylase of SIR2 family [Methylobacterium extorquens DM4]

││││││││││││││││││││││││││││││││││└┬─

fig|419610.8.peg.2025         ⌘ NAD-dependent protein deacetylase of SIR2 family [Methylobacterium extorquens PA1]

│││││││││││││││││││││││││││││││││││└─

fig|882800.3.peg.765  ✚        NAD-dependent protein deacetylase of SIR2 family [Methylobacterium extorquens DSM 13060]

│││││││││││││││││││││││││││││││││┌─

fig|48935.1.peg.3849         ⌘ NAD-dependent protein deacetylase of SIR2 family [Novosphingobium aromaticivorans]

│││││││││││││││││││││││││││││││┌─┴─

fig|279238.18.peg.3         ⌘ NAD-dependent protein deacetylase of SIR2 family [Novosphingobium aromaticivorans DSM 12444]

│││││││││││││││││││││┌─┤││││││┌┴──

fig|317655.9.peg.2613  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Sphingopyxis alaskensis RB2256]

│││││││││││││││││││││││││││││┌┴───

fig|161528.3.peg.2165         ⌘ NAD-dependent protein deacetylase of SIR2 family [Erythrobacter sp. SD-21]

││││││││││││││││││││││││││││┌┴─┬──

fig|237727.3.peg.2264  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Erythrobacter sp. NAP1]

│││││││││││││││││││││││││││┌┤││└──

fig|314225.3.peg.911  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Erythrobacter litoralis HTCC2594]

││││││││││││││││││││││││││││└───

fig|685035.3.peg.1130         ⌘ NAD-dependent protein deacetylase of SIR2 family [Citromicrobium bathyomarinum JL354]

│││││││││││││││││││││││││┌─┤│││││┌─

fig|196162.12.peg.527         ⌘ NAD-dependent protein deacetylase of SIR2 family [Nocardioides sp. JS614]

│││││││││││││││││││││││││││└┬────┴─

fig|196162.6.peg.489         ⌘ NAD-dependent protein deacetylase of SIR2 family [Nocardioides sp. JS614]

││││││││││││││││││││││││││││└─┬────

fig|392499.14.peg.659  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Sphingomonas wittichii RW1]

││││││││││││││││││││││││┌┤││││└┬──

fig|452662.3.peg.1840         ⌘ NAD-dependent protein deacetylase of SIR2 family [Sphingobium japonicum UT26S]

│││││││││││││││││││││││││││││││└──

fig|314266.4.peg.476         ⌘ NAD-dependent protein deacetylase of SIR2 family [Sphingomonas sp. SKA58]

│││││││││││││││││││││││││└──┬──

fig|287752.3.peg.3733  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Aurantimonas manganoxydans SI85-9A1]

││││││││││││││││││││││││││││└────

fig|314231.3.peg.469         ⌘ NAD-dependent protein deacetylase of SIR2 family [Fulvimarina pelagi HTCC2506]

││││││││││││││││││││││││││││││││┌──

fig|349102.13.peg.3332  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodobacter sphaeroides ATCC 17025]

│││││││││││││││││││││││└┤││││┌──┴─

fig|349101.6.peg.4249  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodobacter sphaeroides ATCC 17029]

││││││││││││││││││││││││││││┌┴────

fig|391593.3.peg.135         ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseobacter sp. CCS2]

│││││││││││││││││││││││││││┌┴──

fig|398580.3.peg.2596  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Dinoroseobacter shibae DFL 12]

│││││││││││││││││││││││││┌─┴────

fig|314271.3.peg.2828  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodobacterales bacterium HTCC2654]

││││││││││││││││││││││││││┌────

fig|272942.6.peg.3165         ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodobacter capsulatus SB1003]

││││││││││││││││││││││││└┤││││││││┌─

fig|318586.5.peg.4381         ⌘ NAD-dependent protein deacetylase of SIR2 family [Paracoccus denitrificans PD1222]

│││││││││││││││││││││││││││││┌────┴─

fig|318586.4.peg.4190         ⌘ NAD-dependent protein deacetylase of SIR2 family [Paracoccus denitrificans PD1222]

││││││││││││││││││││││││││││┌┴───

fig|314256.5.peg.1437         ⌘ NAD-dependent protein deacetylase of SIR2 family [Oceanicola granulosus HTCC2516]

│││││││││││││││││││││││││└┤┌┴────

fig|89187.6.peg.299  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseovarius nubinhibens ISM]

││││││││││││││││││││││││││││││││││┌─

fig|314267.6.peg.2020  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Sulfitobacter sp. NAS-14.1]

││││││││││││││││││││┌┤│││││││││││┌┴─

fig|52598.3.peg.3589  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Sulfitobacter sp. EE-36]

││││││││││││││││││││││││││││││││┌┴─

fig|391589.3.peg.1775  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseobacter sp. GAI101]

│││││││││││││││││││││││││││││││┌┴─

fig|391624.3.peg.3066         ⌘ NAD-dependent protein deacetylase of SIR2 family [Oceanibulbus indolifex HEL-45]

││││││││││││││││││││││││││└┤│┌─┴┬─

fig|391595.3.peg.3903         ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseobacter litoralis Och 149]

││││││││││││││││││││││││││││││││└┬─

fig|375451.6.peg.1577         ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseobacter denitrificans OCh 114]

││││││││││││││││││││││││││││┌┤│││└─

fig|375451.14.peg.1621         ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseobacter denitrificans OCh 114]

│││││││││││││││││││││││││││││└───

fig|351016.3.peg.985         ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseobacter sp. AzwK-3b]

│││││││││││││││││││││││││││││││││┌─

fig|292414.1.peg.2781         ⌘ NAD-dependent protein deacetylase of SIR2 family [Silicibacter sp. TM1040]

│││││││││││││││││││││││││││└┤││┌─┴─

fig|292414.10.peg.1549         ⌘ NAD-dependent protein deacetylase of SIR2 family [Ruegeria sp. TM1040]

││││││││││││││││││││││││││││││┌┴──

fig|644076.3.peg.4128         ⌘ NAD-dependent protein deacetylase of SIR2 family [Silicibacter sp. TrichCH4B]

│││││││││││││││││││││││││││││┌┴┬─────

fig|388399.4.peg.3582         ⌘ NAD-dependent protein deacetylase of SIR2 family [Sagittula stellata E-37]

│││││││││││││││││││││││││││││││└────

fig|388739.3.peg.3068         ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseobacter sp. SK209-2-6]

││││││││││││││││││││││││││││└┤││┌─

fig|501479.3.peg.780         ⌘ NAD-dependent protein deacetylase of SIR2 family [Citreicella sp. SE45]

││││││││││││││││││││││││││││││┌─┴─

fig|314265.3.peg.2163         ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseovarius sp. HTCC2601]

│││││││││││││││││││││││││││││└┤┌────

fig|314262.3.peg.2219         ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseobacter sp. MED193]

││││││││││││││││││││││││││││││└┤│┌──

fig|467661.3.peg.2634         ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodobacteraceae bacterium KLH11]

│││││││││││││││││││││││││││││││└┬┴──

fig|644107.3.peg.1311         ⌘ NAD-dependent protein deacetylase of SIR2 family [Silicibacter lacuscaerulensis ITI-1157]

││││││││││││││││││││││││││││││││└┬───

fig|246200.7.peg.993  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Ruegeria pomeroyi DSS-3]

│││││││││││││││││││││││││││││││││└┬────

fig|252305.3.peg.4214  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Oceanicola batsensis HTCC2597]

││││││││││││││││││││││││││││││││││└──

fig|439496.3.peg.1649         ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodobacterales bacterium Y4I]

│││││││││││││││││││││││││┌───

fig|314275.6.peg.2102  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Alteromonas macleodii 'Deep ecotype']

│││││││││││││││││││││││┌─┴─────

fig|342610.6.peg.2201  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudoalteromonas atlantica T6c]

│││││││││││││││││││││└─┤│││┌─────

fig|862908.3.peg.1306  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Bacteriovorax marinus SJ]

││││││││││││││││││││││││┌──┴───────

fig|58051.5.peg.4070         ⌘ NAD-dependent protein deacetylase of SIR2 family [Moritella sp. PE36]

│││││││││││││││││││││││└┤┌──────

fig|203122.15.peg.1604  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Saccharophagus degradans 2-40]

│││││││││││││││││││┌┤│││││││││││││┌─

fig|314282.3.peg.1688         ⌘ NAD-dependent protein deacetylase of SIR2 family [Psychromonas sp. CNPT3]

││││││││││││││││││││││││└┤│││┌────┴─

fig|314282.5.peg.757         ⌘ NAD-dependent protein deacetylase of SIR2 family [Psychromonas sp. CNPT3]

││││││││││││││││││││││││││┌──┴─────

fig|357804.5.peg.1352  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Psychromonas ingrahami ingrahamii 37]

│││││││││││││││││││││││││└┤│││┌───

fig|318161.14.peg.1559  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella denitrificans OS217]

││││││││││││││││││││││││││└───┤┌──

fig|326297.10.peg.1477  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella amazonensis SB2B]

││││││││││││││││││││││││││││││││┌──

fig|318167.10.peg.2255  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella frigidimarina NCIMB 400]

││││││││││││││││││││││││││││││└┤│││││┌─

fig|314608.4.peg.3786         ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella benthica KT99]

││││││││││││││││││││││││││││││││││││┌┴─

fig|392500.6.peg.1907  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella woodyi ATCC 51908]

│││││││││││││││││││││││││││││││││││┌┴─

fig|637905.5.peg.2627         ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella violacea DSS12]

│││││││││││││││││││││││││││││││└┤│┌┴─

fig|425104.7.peg.2990  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella sediminis HAW-EB3]

│││││││││││││││││││││││││││││││││┌┴┬─

fig|323850.3.peg.439  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella sp. PV-4]

│││││││││││││││││││││││││││││││││││└┬─

fig|225849.4.peg.2704  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella piezotolerans WP3]

││││││││││││││││││││││││││││││││││││└┬─

fig|398579.7.peg.1875  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella pealeana ATCC 700345]

│││││││││││││││││││││││││││││││││││││└─

fig|458817.8.peg.2603  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella halifaxensis HAW-EB4]

││││││││││││││││││┌┤││││││││││││└┤│││┌─

fig|60481.13.peg.1775  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella sp. MR-7]

││││││││││││││││││││││││││││││││││││┌┴─

fig|60480.16.peg.1564  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella sp. MR-4]

│││││││││││││││││││││││││││││││││││┌┴─

fig|94122.6.peg.2007  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella sp. ANA-3]

││││││││││││││││││││││││││││││││││┌┴─

fig|211586.1.peg.1768  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella oneidensis MR-1]

│││││││││││││││││││││││││││││││││└┤│┌─

fig|399804.3.peg.2646  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella putrefaciens 200]

││││││││││││││││││││││││││││││││││└┬┴─

fig|351745.9.peg.1818  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella sp. W3-18-1]

│││││││││││││││││││││││││││││││││││└┬─

fig|402882.10.peg.2664  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella baltica OS185]

││││││││││││││││││││││││││││││││││││└┬─

fig|407976.7.peg.1903         ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella baltica OS223]

│││││││││││││││││┌┤││││││││││││││││││└┬─

fig|399599.8.peg.2708  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella baltica OS195]

││││││││││││││││││││││││││││││││││││││└─

fig|693970.3.peg.2750  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Shewanella baltica OS117]

││││││││││││││││││││└┬──────────

fig|59374.8.peg.490  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Fibrobacter succinogenes subsp. succinogenes S85]

│││││││││││││││││││││└───┬────

fig|272568.11.peg.271  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Gluconacetobacter diazotrophicus PAl 5]

│││││││││││││││││││││││││└───

fig|714995.3.peg.211         ⌘ NAD-dependent protein deacetylase of SIR2 family [Gluconacetobacter hansenii ATCC 23769]

│││││││││││││┌───┤│└┬─────

fig|638300.3.peg.2206         ⌘ NAD-dependent protein deacetylase of SIR2 family [Cardiobacterium hominis ATCC 15826]

││││││││││││││││││││└──────

fig|246195.4.peg.1030  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Dichelobacter nodosus VCS1703A]

││││││││││││││││││└───────────────────

fig|582402.5.peg.41         ⌘ NAD-dependent protein deacetylase of SIR2 family [Hirschia baltica ATCC 49814]

│││││││││││││││││││┌─────

fig|264462.1.peg.2547  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Bdellovibrio bacteriovorus HD100]

│││││││││┌───┤│││└┬┴───────

fig|243090.1.peg.4685  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pirellula sp. 1]

││││││││││││││││││└────────┬─

fig|314260.3.peg.815         ⌘ NAD-dependent protein deacetylase of SIR2 family [Parvularcula bermudensis HTCC2503]

│││││││││││││││││││││││││││└─

fig|314260.5.peg.797  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Parvularcula bermudensis HTCC2503]

│││││││││││││└─┬────────

fig|456827.3.peg.848         ⌘ NAD-dependent protein deacetylase of SIR2 family [Cloacamonas acidaminovorans]

││││││││┌┤│││││└──┬─────────

fig|240015.3.peg.2219         ⌘ NAD-dependent protein deacetylase of SIR2 family [Acidobacterium capsulatum ATCC 51196]

││││││││││││││││││└───────┬─

fig|246197.24.peg.3283         ⌘ NAD-dependent protein deacetylase of SIR2 family [Myxococcus xanthus DK 1622]

││││││││││││││││││││││││││└─

fig|246197.19.peg.2961  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Myxococcus xanthus DK 1622]

│││││││┌┤└───────

fig|643562.5.peg.2399         ⌘ NAD-dependent protein deacetylase of SIR2 family [Desulfovibrio aespoeensis Aspo-2]

││││││││││││││┌──────────

fig|543728.3.peg.303         ⌘ NAD-dependent protein deacetylase of SIR2 family [Variovorax paradoxus S110]

││││││││└──┬──┴─────────────

fig|446470.5.peg.2557  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Stackebrandtia nassauensis DSM 44728]

│││││││││││└─┬──────────────────

fig|446465.4.peg.2185  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Brachybacterium faecium DSM 4810]

│││││││││││││└────┬───────

fig|329726.14.peg.3464         ⌘ NAD-dependent protein deacetylase of SIR2 family [Acaryochloris marina MBIC11017]

││││││││││││││││││└─────┬─

fig|316274.7.peg.4212         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

│││││┌─┤││││││││││││││││└─

fig|316274.3.peg.4178         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

│││││││││││││││││││││││││││││││┌─

fig|521674.6.peg.1827         ⌘ NAD-dependent protein deacetylase of SIR2 family [Planctomyces limnophilus DSM 3776]

│││││││││││││┌─────────────────┴─

fig|521674.5.peg.4017  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Planctomyces limnophilus DSM 3776]

││││││││┌────┴──────┬────

fig|517417.5.peg.1051  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Chlorobaculum parvum NCIB 8327]

││││││││││││││││││││└───

fig|331678.5.peg.571  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Chlorobium phaeobacteroides BS1]

│││││││└┤││││││┌─

fig|335543.6.peg.3673         ⌘ NAD-dependent protein deacetylase of SIR2 family [Syntrophobacter fumaroxidans MPOB]

││││││││││┌────┴─

fig|335543.9.peg.4229         ⌘ NAD-dependent protein deacetylase of SIR2 family [Syntrophobacter fumaroxidans MPOB]

│││││││││││││││││││┌─

fig|448385.11.peg.545         ⌘ NAD-dependent protein deacetylase of SIR2 family [Sorangium cellulosum So ce 56]

││││││││└─┤│┌──────┴─

fig|448385.16.peg.647         ⌘ NAD-dependent protein deacetylase of SIR2 family [Sorangium cellulosum 'So ce 56']

││││││││││││││││││││││││┌─

fig|9606.3.peg.26474         ⌘ NAD-dependent protein deacetylase of SIR2 family [Homo sapiens (Human)]

│││││││││││││││││││││││┌┴─

fig|9606.3.peg.26473         ⌘ NAD-dependent protein deacetylase of SIR2 family [Homo sapiens (Human)]

││││││││││└─┤││││││┌───┴─

fig|10090.3.peg.27756         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mus musculus (House mouse)]

││││││││││││││┌────┴────

fig|10228.3.peg.4164         Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Trichoplax adhaerens]

│││││││││││││││││││││││┌──────

fig|578458.3.peg.5345         ⌘ Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Schizophyllum commune H4-8]

││││││││││││└─┤││││┌───┴────────

fig|578458.3.peg.1591         ⌘ Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Schizophyllum commune H4-8]

│││││││││││││││││││││││││││││┌─────────

fig|336722.3.peg.6508         ⌘ Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Mycosphaerella graminicola IPO323]

││││││││││││││└────┤││││││││┌┴───

fig|383855.3.peg.2408         ⌘ Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Mycosphaerella fijiensis CIRAD86]

││││┌┤││││││││││││││││││││┌─┴───

fig|336722.3.peg.5152         ⌘ Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Mycosphaerella graminicola IPO323]

│││││││││││││││││││└───┬──┴───

fig|701091.3.peg.5801         ⌘ Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Cochliobolus heterostrophus C5]

│││││││││││││││││││││││└──┬───────

fig|413071.3.peg.3269         Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Trichoderma virens Gv29-8]

││││││││││││││││││││││││││└┬───

fig|35720.3.peg.6940         Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Thielavia terrestris]

│││││││││││││││││││││││││││└──┬─

fig|510953.3.peg.8413         ⌘ Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Neurospora discreta FGSC 8579 matA]

││││││││││││││││││││││││││││││└─

fig|510951.3.peg.7563         ⌘ Sirtuin 5 and related class III sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Neurospora tetrasperma FGSC 2508 mat A]

││││││││││││││││┌─

fig|349106.5.peg.655         ⌘ NAD-dependent protein deacetylase of SIR2 family [Psychrobacter sp. PRwf-1]

││││││││││││┌───┴─

fig|349106.9.peg.653         ⌘ NAD-dependent protein deacetylase of SIR2 family [Psychrobacter sp. PRwf-1]

│││││││││││┌┴───────

fig|553217.3.peg.1013         ⌘ NAD-dependent protein deacetylase of SIR2 family [Enhydrobacter aerosaccus SK60]

││││││┌────┴────

fig|335284.3.peg.1247  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Psychrobacter cryohalolentis K5]

│││││││││││││││││││┌─

fig|262724.1.peg.1020         ⌘ NAD-dependent protein deacetylase of SIR2 family [Thermus thermophilus HB27]

││││││││││││││││││┌┴─

fig|300852.3.peg.1671         ⌘ NAD-dependent protein deacetylase of SIR2 family [Thermus thermophilus HB8]

││││││││││││││││┌─┴─

fig|498848.5.peg.328         ⌘ NAD-dependent protein deacetylase of SIR2 family [Thermus aquaticus Y51MC23]

││││││││││││││┌─┴─┬──

fig|526227.4.peg.969  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Meiothermus silvanus DSM 9946]

││││││││││││┌─┤│││└───

fig|504728.5.peg.1112  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Meiothermus ruber DSM 1279]

││││││││┌───┤│└──────

fig|649638.3.peg.2834         ⌘ NAD-dependent protein deacetylase of SIR2 family [Truepera radiovictrix DSM 17093]

│││││└┤│││││└──┬──

fig|319795.16.peg.850  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Deinococcus geothermalis DSM 11300]

│││││││││││││││└─┬───

fig|243230.17.peg.182  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Deinococcus radiodurans R1]

│││││││││││││││││└──

fig|546414.3.peg.248         ⌘ NAD-dependent protein deacetylase of SIR2 family [Deinococcus deserti VCD115]

│││││││││┌────

fig|266117.10.peg.1378  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Rubrobacter xylanophilus DSM 9941]

││││││││││││││││││││││││││┌─

fig|316274.3.peg.3218         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

││││││││││││││││││││┌─────┴─

fig|316274.7.peg.3259         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

│││││││││││││││┌────┴────┬─

fig|357808.3.peg.1209  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseiflexus sp. RS-1]

││││││└─┤││││││││││││││││└─

fig|383372.6.peg.1807  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseiflexus castenholzii DSM 13941]

││││││││││││││┌┤││││││││││││┌─

fig|316274.3.peg.2485         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

│││││││││││││││└───┬────────┴─

fig|316274.7.peg.2523         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

│││││││││││││┌┤││││└─────────┬─

fig|316274.7.peg.704         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

│││││││││││││││││││││││││││││└─

fig|316274.3.peg.701         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

││││││││││││┌┤└───────┬─

fig|316274.7.peg.3258         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

││││││││││││││││││││││└─

fig|316274.3.peg.3217         ⌘ NAD-dependent protein deacetylase of SIR2 family [Herpetosiphon aurantiacus ATCC 23779]

│││││││││││││└┬─────

fig|485913.3.peg.5316         ⌘ NAD-dependent protein deacetylase of SIR2 family [Ktedonobacter racemifer DSM 44963]

││││││││└┤││││└┬──────────

fig|379066.3.peg.2426         ⌘ NAD-dependent protein deacetylase of SIR2 family [Gemmatimonas aurantiaca T-27]

│││││││││││┌┤││└─┬──────

fig|530564.3.peg.4011         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pirellula staleyi DSM 6068]

│││││││││││││││││└───┬──

fig|324602.4.peg.2877  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Chloroflexus aurantiacus J-10-fl]

│││││││││││││││││││││└─

fig|326427.4.peg.945  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Chloroflexus aggregans DSM 9485]

││││││││││┌┤└──────

fig|320771.5.peg.1552         ⌘ NAD-dependent protein deacetylase of SIR2 family [bacterium Ellin514]

││││││││││││││││││││┌─

fig|354.1.peg.426         ⌘ NAD-dependent protein deacetylase of SIR2 family [Azotobacter vinelandii]

││││││││││││┌───────┴─

fig|322710.5.peg.3120  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Azotobacter vinelandii DJ]

│││││││││││└┤││││││┌─

fig|349124.5.peg.1566         ⌘ NAD-dependent protein deacetylase of SIR2 family [Halorhodospira halophila SL1]

││││││││││││└─┬────┴─

fig|349124.8.peg.1568         ⌘ NAD-dependent protein deacetylase of SIR2 family [Halorhodospira halophila SL1]

││││││││││││││└─────┬─

fig|187272.6.peg.1940         ⌘ NAD-dependent protein deacetylase of SIR2 family [Alkalilimnicola ehrlichii MLHE-1]

││││││││││││││││││││└─

fig|187272.10.peg.2035         ⌘ NAD-dependent protein deacetylase of SIR2 family [Alkalilimnicola ehrlichii MLHE-1]

│││││││││││││││││││││┌─

fig|309807.19.peg.2671  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salinibacter ruber DSM 13855]

│││││││││││││││┌─────┴─

fig|146919.6.peg.2738         ⌘ NAD-dependent protein deacetylase of SIR2 family [Salinibacter ruber]

│││││││││└┤│┌──┴───

fig|518766.5.peg.1670  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Rhodothermus marinus DSM 4252]

│││││││││││┌┴─────┬────────

fig|522306.3.peg.1349         ⌘ NAD-dependent protein deacetylase of SIR2 family [Accumulibacter phosphatis clade IIA str. UW-1]

││││││││││││││││││└──────────────

fig|96561.3.peg.3221  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Desulfococcus oleovorans Hxd3]

││││││││││││││││┌─

fig|383372.6.peg.1806  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseiflexus castenholzii DSM 13941]

││││││││││││┌───┴──

fig|357808.3.peg.1208  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Roseiflexus sp. RS-1]

││││││││││││││││││││││││││┌─

fig|398578.3.peg.4009         ⌘ NAD-dependent protein deacetylase of SIR2 family [Delftia acidovorans SPH-1]

│││││││││││││││││││││││┌──┴─

fig|398578.5.peg.4043         ⌘ NAD-dependent protein deacetylase of SIR2 family [Delftia acidovorans SPH-1]

│││││││││││││││││││││┌─┴────┬─

fig|399795.3.peg.1688         ⌘ NAD-dependent protein deacetylase of SIR2 family [Comamonas testosteroni KF-1]

││││││││││││││││││││┌┤││││││└─

fig|688245.4.peg.3129  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Comamonas testosteroni CNB-2]

│││││││││││││││││││││└┬─

fig|535289.3.peg.1648         ⌘ NAD-dependent protein deacetylase of SIR2 family [Diaphorobacter sp. TPSY]

││││││││││└┤│││││││┌┤│└┬─

fig|232721.9.peg.2464         ⌘ NAD-dependent protein deacetylase of SIR2 family [Acidovorax sp. JS42]

│││││││││││││││││││││││└─

fig|232721.5.peg.2317         ⌘ NAD-dependent protein deacetylase of SIR2 family [Acidovorax sp. JS42]

││││││││││││││││││┌┤└──

fig|596153.4.peg.2632  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Alicycliphilus denitrificans BC]

│││││││││││││││││││└───┬─

fig|643561.3.peg.977  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Acidovorax avenae subsp. avenae ATCC 19860]

││││││││││││││││┌─┤││││└┬─

fig|397945.5.peg.2568         ⌘ NAD-dependent protein deacetylase of SIR2 family [Acidovorax avenae subsp. citrulli AAC00-1]

││││││││││││││││││││││││└─

fig|1154764.4.peg.1876  ✚        NAD-dependent protein deacetylase of SIR2 family [Acidovorax citrulli ZJU1106]

││││││││││││││││││└──────┬─

fig|395495.3.peg.1831         ⌘ NAD-dependent protein deacetylase of SIR2 family [Leptothrix cholodni SP-6]

│││││││││││││││││││││││││└─

fig|395495.5.peg.1918         ⌘ NAD-dependent protein deacetylase of SIR2 family [Leptothrix cholodnii SP-6]

│││││││││││││┌──┤│││││┌─

fig|381666.6.peg.2754         ⌘ NAD-dependent protein deacetylase of SIR2 family [Ralstonia eutropha H16]

│││││││││││└┤││││││││┌┴─

fig|164546.7.peg.1851         ⌘ NAD-dependent protein deacetylase of SIR2 family [Cupriavidus taiwanensis]

││││││││││││││││││││┌┴─

fig|264198.3.peg.2756  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Ralstonia eutropha JMP134]

│││││││││││││││││││┌┴──

fig|266264.4.peg.2488  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Cupriavidus metallidurans CH34]

││││││││││││││││└──┤│││┌─

fig|428406.5.peg.1772         ⌘ NAD-dependent protein deacetylase of SIR2 family [Ralstonia pickettii 12D]

│││││││││││││││││││└──┬┴─

fig|402626.5.peg.2278         ⌘ NAD-dependent protein deacetylase of SIR2 family [Ralstonia pickettii 12J]

││││││││││││││││││││││└┬─

fig|342110.4.peg.2613         ⌘ NAD-dependent protein deacetylase of SIR2 family [Ralstonia solanacearum UW551]

│││││││││││││││││││││││└┬─

fig|267608.1.peg.1230         ⌘ NAD-dependent protein deacetylase of SIR2 family [Ralstonia solanacearum GMI1000]

││││││││││││││││││││││││└─

fig|267608.8.peg.1249  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Ralstonia solanacearum GMI1000]

│││││││││││││││││││││││││││││││││││┌─

fig|264730.3.peg.3739         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas syringae pv. phaseolicola 1448A]

│││┌┤│││││││││││││││││││││││││││││┌┴─

fig|264730.9.peg.4519         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas syringae pv. phaseolicola 1448A]

│││││││││││││││││││││││││││││││┌──┴─

fig|546231.4.peg.2939  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas syringae pv. tomato T1]

││││││││││││││││││││││││││││││┌┴──┬─

fig|223283.1.peg.4564         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas syringae pv. tomato str. DC3000]

││││││││││││││││││││││││││││┌─┤│││└─

fig|223283.9.peg.4793  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas syringae pv. tomato str. DC3000]

││││││││││││││││││││││││││││││└──┬─

fig|223283.9.peg.592         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas syringae pv. tomato str. DC3000]

│││││││││││││││││││││││││││┌┤││││└─

fig|223283.1.peg.569  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas syringae pv. tomato str. DC3000]

││││││││││││││││││││││││││││└───┬─

fig|160488.1.peg.5332         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas putida KT2440]

││││││││││││└┤│││││││││┌───┤││││└┬─

fig|390235.5.peg.35         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas putida W619]

│││││││││││││││││││││││││││││││││└─

fig|390235.3.peg.33         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas putida W619]

│││││││││││││││││││││┌─┤│││└──┬─

fig|390235.5.peg.2372         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas putida W619]

││││││││││││││││││││││││││││││└─

fig|390235.3.peg.2342         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas putida W619]

│││││││││││││││││││┌─┤│└──────

fig|216595.4.peg.94         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas fluorescens SBW25]

││││││││││││││││││││││┌─────

fig|591153.3.peg.4867         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas syringae pv. syringae FF5]

│││││││││││││││││││││└┤┌───

fig|379731.4.peg.1969  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas stutzeri A1501]

││││││││││││││││││││││└┤┌────

fig|220664.3.peg.3538  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas fluorescens Pf-5]

│││││││││││││││││││││││└┤┌─────

fig|384676.9.peg.2232  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas entomophila L48]

││││││││││││││││││││││││└┤││┌─

fig|381754.6.peg.4065  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas aeruginosa PA7]

│││││││││││││││││┌─┤│││││└──┤│┌─

fig|1163396.3.peg.4178  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas aeruginosa CI27]

││││││││││││││││││││││││││││└┬┴─

fig|350704.7.peg.106  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas aeruginosa C3719]

│││││││││││││││││││││││││││││└┬─

fig|350703.9.peg.114  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas aeruginosa 2192]

││││││││││││││││││││││││││││││└┬─

fig|388272.4.peg.1675         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas aeruginosa PACS2]

│││││││││││││││┌─┤│││││││││││││└─

fig|557722.4.peg.4322  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudomonas aeruginosa LESB58]

│││││││││││││││││││└┬────

fig|243233.7.peg.1656  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Methylococcus capsulatus str. Bath]

││││││││││││││││││││└────

fig|742159.3.peg.5504         ⌘ NAD-dependent protein deacetylase of SIR2 family [Achromobacter piechaudii ATCC 43553]

│││││││││││││││││└─┬───

fig|369723.3.peg.2825  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Salinispora tropica CNB-440]

│││││││││││││└─┤│││└───┬─

fig|644283.3.peg.760  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Micromonospora aurantiaca ATCC 27029]

│││││││││││││││││││││││└─

fig|648999.4.peg.5102  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Micromonospora sp. L5]

│││││││││││││││││┌──────

fig|465515.4.peg.597  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Micrococcus luteus NCTC 2665]

││││││││││││││││││┌─────────

fig|1001738.3.peg.3696  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium abscessus 6G-1108]

│││││││││││││││││││┌──────

fig|478801.4.peg.1410  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Kytococcus sedentarius DSM 20547]

│││││││││││││││└─┤││││││││││││││││││┌─

fig|1232381.3.peg.819         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium glutamicum SCgG1]

││││││││││││││││││││││││││││││││┌───┴─

fig|196627.4.peg.746  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium glutamicum ATCC 13032]

││││││││││││││││││││││││││││││┌─┴─┬─

fig|196164.6.peg.677  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium efficiens YS-314]

│││││││││││││││││└┤││││││││││┌┤│││└─

fig|196164.1.peg.653         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium efficiens YS-314]

││││││││││││││││││││││││││││││└─┬────

fig|645127.4.peg.1339         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium kroppenstedtii DSM 44385]

││││││││││││││││││││││││││││││││└┬────

fig|504474.4.peg.76  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium urealyticum DSM 7109]

││││││││││││││││││││││││││││┌┤│││└─┬─

fig|306537.10.peg.76  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium jeikeium K411]

│││││││││││││││││││││││││││││││││││└─

fig|525262.3.peg.375         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium jeikeium ATCC 43734]

│││││││││││││││││││││││││││┌┤└───┬─

fig|553207.3.peg.300         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium matruchotii ATCC 14266]

││││││││││││││││││└┤│││││││││││││└─

fig|566549.5.peg.205         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium matruchotii ATCC 33806]

││││││││││││││││││││││││││││└┬──────

fig|649754.3.peg.796         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium ammoniagenes DSM 20306]

│││││││││││││││││││││││┌───┤│└┬────

fig|525268.3.peg.1630         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium striatum ATCC 6940]

││┌┤││││││││││││││││││││││││││└┬────

fig|548476.3.peg.137  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium aurimucosum ATCC 700975]

│││││││││││││││││││││││││││││││└───

fig|585529.3.peg.386         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium genitalium ATCC 33030]

│││││││││││││││││││││┌─┤│││└──────┬─

fig|548477.4.peg.1845         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium glucuronolyticum ATCC 51867]

││││││││││││││││││││││││││││││││││└─

fig|548478.3.peg.86         ⌘ NAD-dependent protein deacetylase of SIR2 family [Corynebacterium glucuronolyticum ATCC 51866]

│││││││││││││││││││││││└─┬────

fig|526226.5.peg.4871  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Gordonia bronchialis DSM 43247]

│││││││││││││││││││││││││└────┬─

fig|521096.4.peg.1409  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Tsukamurella paurometabola DSM 20162]

││││││││││││││││││││││││││││││└─

fig|521096.6.peg.1298         ⌘ NAD-dependent protein deacetylase of SIR2 family [Tsukamurella paurometabola DSM 20162]

││││││││││││││││││││││││││││││┌─

fig|164757.7.peg.4249         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium sp. JLS]

│││││││││││││││││││└─┤│││││││┌┴─

fig|164757.10.peg.4328         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium sp. JLS]

││││││││││││││││││││││││││││┌┴┬─

fig|189918.11.peg.4660         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium sp. KMS]

│││││││││││││││││││││││││││┌┤│└─

fig|164756.6.peg.3865  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium sp. MCS]

││││││││││││││││││││││││││││└─┬─

fig|350054.11.peg.2180  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium gilvum PYR-GCK]

│││││││││││││││││││││││││┌─┤││└┬─

fig|350058.5.peg.4494         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium vanbaaleni vanbaalenii PYR-1]

│││││││││││││││││││││││││││││││└─

fig|350058.8.peg.4650         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium vanbaalenii PYR-1]

│││││││││││││││││││││││││││└┬─

fig|246196.19.peg.5049         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium smegmatis str. MC2 155]

│││││││││││││││││││││└───┤││└─

fig|246196.1.peg.5159         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium smegmatis str. MC2 155]

│││││││││││││││││││││││││││┌──

fig|272631.1.peg.930  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium leprae TN]

│││││││││││││││││││││││││││││││┌─

fig|1078011.3.peg.81  ✚        NAD-dependent protein deacetylase of SIR2 family [Mycobacterium avium subsp. avium DT 78]

││││││││││││││││││││││││││││││┌┴─

fig|553481.3.peg.1118         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium avium subsp. avium ATCC 25291]

│││││││││││││││││││││││││└─┤│┌┴─

fig|262316.1.peg.2633  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium avium subsp. paratuberculosis str. k10]

││││││││││││││││││││││││││││┌┴─

fig|525368.3.peg.2324         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium parascrofulaceum ATCC BAA-614]

││││││││││││││││││││││││││││││││┌─

fig|216594.1.peg.2710         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium marinum M]

│││││││││││││││││││││││││││└┤││┌┴─

fig|216594.6.peg.4619         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium marinum M]

││││││││││││││││││││││││││││││┌┴─

fig|362242.7.peg.1227         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium ulcerans Agy99]

│││││││││││││││││││││││││││││┌┴──

fig|557599.3.peg.1620         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium kansasii ATCC 12478]

││││││││││││││││││││││││││││└┤┌─

fig|1765.158.peg.10337  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium bovis str. 09-4305]

│││││││││││││││││││││││││││││└┤┌─

fig|611304.3.peg.4117         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium tuberculosis K85]

││││││││││││││││││││││││││││││└┤┌─

fig|1806.1.peg.3148         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium microti OV254]

│││││││││││││││││││││││││││││││└┼─

fig|233413.1.peg.1167  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium bovis AF2122/97]

││││││││││││││││││││││││││││││││└─

fig|410289.13.peg.1207  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Mycobacterium bovis BCG str. Pasteur 1173P2]

││││└───────┬─

fig|234267.13.peg.7363         ⌘ NAD-dependent protein deacetylase of SIR2 family [Solibacter usitatus Ellin6076]

││││││││││││└─

fig|234267.9.peg.6689         ⌘ NAD-dependent protein deacetylase of SIR2 family [Solibacter usitatus Ellin6076]

│││││┌───────────

fig|436308.3.peg.1773         ⌘ NAD-dependent protein deacetylase of SIR2 family [Nitrosopumilus maritimus SCM1]

│││││││││││││││││││││││││││││┌─

fig|447217.4.peg.4160  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Anaeromyxobacter sp. K]

││││││││││││││││││││││││││││┌┴─

fig|455488.5.peg.4206  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Anaeromyxobacter dehalogenans 2CP-1]

│││││││││││││││││││││││││││┌┴─

fig|290397.13.peg.4015  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Anaeromyxobacter dehalogenans 2CP-C]

│││││││││││││││││││││││┌───┴──

fig|404589.4.peg.359  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Anaeromyxobacter sp. Fw109-5]

│││││││││││││││││││││┌─┴┬───────

fig|502025.5.peg.2760  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Haliangium ochraceum DSM 14365]

││││││││││││││││││┌──┤││└───────

fig|391625.5.peg.1350         ⌘ NAD-dependent protein deacetylase of SIR2 family [Plesiocystis pacifica SIR-1]

│││││││││││││││││┌┤││└────────

fig|177437.4.peg.4913         ⌘ NAD-dependent protein deacetylase of SIR2 family [Desulfobacterium autotrophicum HRM2]

││││││││││││││││││└──┬──────

fig|313606.3.peg.2002         ⌘ NAD-dependent protein deacetylase of SIR2 family [Microscilla marina ATCC 23134]

││││││││││││││││┌┤│││└──────

fig|313606.3.peg.2001         ⌘ NAD-dependent protein deacetylase of SIR2 family [Microscilla marina ATCC 23134]

│││└─┤│││││││││││└───┬──────────

fig|391587.3.peg.2813         ⌘ NAD-dependent protein deacetylase of SIR2 family [Kordia algicida OT-1]

││││││││┌───────┤││││└─────

fig|313606.3.peg.4233         ⌘ NAD-dependent protein deacetylase of SIR2 family [Microscilla marina ATCC 23134]

│││││││││││││││││││││││┌────────────────────────────

fig|5786.3.peg.297         ⌘ Sirtuin 4 and related class II sirtuins (SIR2 family); NAD-dependent protein deacetylase of SIR2 family [Dictyostelium purpureum QXDP1]

││││││││││││││││└──────┤││││││││││││┌────

fig|488538.3.peg.2543         ⌘ NAD-dependent protein deacetylase of SIR2 family [alpha proteobacterium IMCC1322]

│││││││││││││││││││││││└────────────┤│┌───

fig|87626.5.peg.947  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudoalteromonas tunicata D2]

││││││││││││││││││││││││││││││││││││└─┤│┌─

fig|566466.4.peg.2355         ⌘ NAD-dependent protein deacetylase of SIR2 family [gamma proteobacterium NOR5-3]

│││││││┌┤│││││││││││││││││││││││││││││└┬┴──

fig|314285.3.peg.3005  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [gamma proteobacterium KT 71]

│││││││││││││││││││││││││││││││││││││││└┬────

fig|207949.3.peg.715         ⌘ NAD-dependent protein deacetylase of SIR2 family [Bermanella marisrubri]

││││││││││││││││││││││││││││││││││││││││└─┬──

fig|326442.4.peg.3000  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pseudoalteromonas haloplanktis TAC125]

││││││││││││││││││││││││││││││││││││││││││└─

fig|156578.3.peg.3258         ⌘ NAD-dependent protein deacetylase of SIR2 family [Alteromonadales bacterium TW-7]

│││││└─┤└────┬──

fig|355277.4.peg.1786  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Leptospira borgpetersenii serovar Hardjo-bovis JB197]

│││││││││││││└─┬─

fig|189518.3.peg.2241  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Leptospira interrogans serovar Lai str. 56601]

│││││││││││││││└─

fig|996847.3.peg.1009  ✚        NAD-dependent protein deacetylase of SIR2 family [Leptospira interrogans serovar Copenhageni str. Fiocruz LV2959]

│││││││││││┌─────

fig|355278.4.peg.732  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Ames)']

│││││││││││││││││││││││││││││││││││││││││┌─

fig|522772.5.peg.1886         ⌘ NAD-dependent protein deacetylase of SIR2 family [Denitrovibrio acetiphilus DSM 12809]

│││││││└───┤│││││││││││││││││┌───────────┴─

fig|522772.6.peg.2895         ⌘ NAD-dependent protein deacetylase of SIR2 family [Denitrovibrio acetiphilus DSM 12809]

││││││││││││││││││││││││││││││││││││││┌──────────────

fig|313606.3.peg.3645         ⌘ NAD-dependent protein deacetylase of SIR2 family [Microscilla marina ATCC 23134]

││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|232721.9.peg.1009         ⌘ NAD-dependent protein deacetylase of SIR2 family [Acidovorax sp. JS42]

│││││││││││└─────────────────┤│││││││││││││┌────────┴─

fig|232721.5.peg.952         ⌘ NAD-dependent protein deacetylase of SIR2 family [Acidovorax sp. JS42]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|269482.4.peg.1264         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia vietnamiensis strain G4]

││││││││││││││││││││││││││││││││││││││││││││┌──────────┴─

fig|269482.11.peg.1586         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia vietnamiensis G4]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|243231.1.peg.3066  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Geobacter sulfurreducens PCA]

│││││││││││││││││││││││││││││└────────┤│││││││││││││││││││││││┌┴─

fig|269799.3.peg.409  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Geobacter metallireducens GS-15]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴────

fig|653733.3.peg.755  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [bacterium S5]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴──

fig|351605.6.peg.972  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Geobacter uraniireducens Rf4]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴┬─────

fig|404589.4.peg.3685  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Anaeromyxobacter sp. Fw109-5]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└───

fig|370438.4.peg.695  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Pelotomaculum thermopropionicum SI]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┤│││││┌─

fig|891.1.peg.3044         ⌘ NAD-dependent protein deacetylase of SIR2 family [Desulfuromonas acetoxidans]

││││││││││││││││││││││││││││││││││││││└────┤│││││││││││││││││┌───┴─

fig|281689.4.peg.658         ⌘ NAD-dependent protein deacetylase of SIR2 family [Desulfuromonas acetoxidans DSM 684]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└┬┴──

fig|891.1.peg.3606         ⌘ NAD-dependent protein deacetylase of SIR2 family [Desulfuromonas acetoxidans]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││┌──┤│└──┬──

fig|443143.3.peg.453  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Geobacter sp. M18]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└┬─

fig|443144.3.peg.1368         ⌘ NAD-dependent protein deacetylase of SIR2 family [Geobacter sp. M21]

││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┤││││││││└─

fig|404380.4.peg.2759  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Geobacter bemidjiensis Bem]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└─────

fig|639282.3.peg.1436         ⌘ NAD-dependent protein deacetylase of SIR2 family [Deferribacter desulfuricans SSM1]

│││││││││││││││││││││││││││││││││││││││││││││││││││┌──┤└───

fig|398767.5.peg.2708         ⌘ NAD-dependent protein deacetylase of SIR2 family [Geobacter lovleyi SZ]

││││││││││││││││││││││││││││││││││││││││││││││││││││││└───┬─

fig|338966.9.peg.2182         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pelobacter propionicus DSM 2379]

││││││││││││││││││││││││││││││││││││││││││││││││││┌┤││││││└─

fig|338966.5.peg.2053         ⌘ NAD-dependent protein deacetylase of SIR2 family [Pelobacter propionicus DSM 2379]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|471857.4.peg.3822  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Saccharomonospora viridis DSM 43017]

┌─┤││││││││││││││││││││││││││││││││││││││││└┤││││││└──┬─┴───

fig|591158.3.peg.7359         ⌘ NAD-dependent protein deacetylase of SIR2 family [Streptomyces sp. AA4]

││││││││││││││││││││││││││││││││││││││││││││││││││││││└┬───

fig|446462.6.peg.346  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Actinosynnema mirum DSM 43827]

│││││││││││││││││││││││││││││││││││││││││││││││││┌┤││││└┬──

fig|102897.3.peg.3227         ⌘ NAD-dependent protein deacetylase of SIR2 family [Frankia sp. EUN1f]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││└─┬─

fig|326424.13.peg.2976         ⌘ NAD-dependent protein deacetylase of SIR2 family [Frankia alni ACN14a]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└─

fig|326424.15.peg.2984         ⌘ NAD-dependent protein deacetylase of SIR2 family [Frankia alni ACN14a]

││││││││││││││││││││││││││││││││││││││││││││││││││└─────

fig|378806.7.peg.7433         ⌘ NAD-dependent protein deacetylase of SIR2 family [Stigmatella aurantiaca DW4/3-1]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|335543.6.peg.3629         ⌘ NAD-dependent protein deacetylase of SIR2 family [Syntrophobacter fumaroxidans MPOB]

││││││││││││││││││││││││││││││││││││││││││││││││┌┤│││┌─────┴─

fig|335543.9.peg.4178         ⌘ NAD-dependent protein deacetylase of SIR2 family [Syntrophobacter fumaroxidans MPOB]

││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴─┬────

fig|525898.4.peg.2353  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Sulfurospirillum deleyianum DSM 6946]

│││││││││││││││││││││││││││││││││││││││││││││││││││┌┤││└───────

fig|360104.9.peg.398  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Campylobacter concisus 13826]

││││││││││││││││││││││││││││││││││││││││││││││││││││└───────┬─

fig|306263.1.peg.341         ⌘ NAD-dependent protein deacetylase of SIR2 family [Campylobacter lari RM2100]

│││││││││││││││││││││││││││││││││││││││││││││││││└─┤││││││││└─

fig|306263.5.peg.872         ⌘ NAD-dependent protein deacetylase of SIR2 family [Campylobacter lari RM2100]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|387093.4.peg.1002         ⌘ NAD-dependent protein deacetylase of SIR2 family [Sulfurovum sp. NBC37-1]

││││││││││││││││││││││││││││││││││││││││││││││││││││┌─────┴─

fig|387093.6.peg.1057         ⌘ NAD-dependent protein deacetylase of SIR2 family [Sulfurovum sp. NBC37-1]

│││││││││││││││││││││││││││││││││││││││││││││││││││└┤││┌──────

fig|391592.5.peg.1669         ⌘ NAD-dependent protein deacetylase of SIR2 family [Caminibacter mediatlanticus TB-2]

││││││││││││││││││││││││││││││││││││││││││││││││││││└┬─┴───

fig|387092.5.peg.544  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Nitratiruptor sp. SB155-2]

│││││││││││││││││││││││││││││││││││││││││││││││││││││└─┬───

fig|123214.3.peg.522         ⌘ NAD-dependent protein deacetylase of SIR2 family [Persephonella marina EX-H1]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││└─┬──

fig|204536.4.peg.236         ⌘ NAD-dependent protein deacetylase of SIR2 family [Sulfurihydrogenibium azorense Az-Fu1]

││││││││││││││││││││││││││││││││││││││││││││└───┤││││││││└──

fig|436114.4.peg.1369  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Sulfurihydrogenibium sp. YO3AOP1]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|374931.9.peg.257  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Haemophilus influenzae PittGG]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|281310.3.peg.174  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Haemophilus influenzae 86-028NP]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌──┴─

fig|521004.3.peg.1313  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Haemophilus influenzae 6P18H1]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴───

fig|669261.3.peg.728         ⌘ NAD-dependent protein deacetylase of SIR2 family [Mannheimia haemolytica serotype A2 str. OVINE]

│││││││││││││││││││││││││││││││││││││││││││││││││││┌───┴───

fig|637911.3.peg.1035         ⌘ NAD-dependent protein deacetylase of SIR2 family [Actinobacillus minor NM305]

││││││││││││││││││││││││││││││││││││││││││││││││││┌┴───────

fig|637911.3.peg.1036         ⌘ NAD-dependent protein deacetylase of SIR2 family [Actinobacillus minor NM305]

│││││││││││││││││││││││││││││││││││││││││││││││││┌┴──────

fig|553217.3.peg.1285         ⌘ NAD-dependent protein deacetylase of SIR2 family [Enhydrobacter aerosaccus SK60]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|266265.5.peg.4894  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia xenovorans LB400]

││││││││││││││││││││││││││││││││││││││││││││││││││││┌────┴─

fig|243261.3.peg.3872         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia sp. Ch1-1]

│││││││││││││││││││││││││││││││││││││││││││││││││││┌┴───

fig|243261.3.peg.6907         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia sp. Ch1-1]

││││││││││││││││││││││││││││││││││││││││││││││││││┌┴─────

fig|391038.7.peg.5812         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia phymatum STM815]

││││││││││││││││││││││││││││││││││││││││││││││││└┤││││││││││┌─

fig|62928.7.peg.240         ⌘ NAD-dependent protein deacetylase of SIR2 family [Azoarcus sp. BH72]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌───┴─

fig|62928.8.peg.241         ⌘ NAD-dependent protein deacetylase of SIR2 family [Azoarcus sp. BH72]

││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─┴────

fig|85643.4.peg.2068  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Thauera sp. MZ1T]

│││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴─────┬─

fig|159087.4.peg.110         ⌘ NAD-dependent protein deacetylase of SIR2 family [Dechloromonas aromatica RCB]

││││││││││││││││││││││││││││││││││││││││││││││││││││┌┤││││││└─

fig|159087.6.peg.6         ⌘ NAD-dependent protein deacetylase of SIR2 family [Dechloromonas aromatica RCB]

│││││││││││││││││││││││││││││││││││││││││││││││││││││└┬─────

fig|76114.8.peg.1604  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Aromatoleum aromaticum EbN1]

│││││││││││││││││││││││││││││││││││││││││││││││││└┤┌┤│└───

fig|522306.3.peg.3187         ⌘ NAD-dependent protein deacetylase of SIR2 family [Accumulibacter phosphatis clade IIA str. UW-1]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││┌────

fig|556268.6.peg.2636         ⌘ NAD-dependent protein deacetylase of SIR2 family [Oxalobacter formigenes HOxBLS]

││││││││││││││││││││││││││││││││││││││││││││││││││││└┬─┴────

fig|556269.4.peg.68         ⌘ NAD-dependent protein deacetylase of SIR2 family [Oxalobacter formigenes OXCC13]

│││││││││││││││││││││││││││││││││││││││││││││││││││││└┬─────

fig|1217666.3.peg.184  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Acinetobacter junii CIP 107470]

││││││││││││││││││││││││││││││││││││││││││││││││││││││└──┬───

fig|365044.20.peg.466         ⌘ NAD-dependent protein deacetylase of SIR2 family [Polaromonas naphthalenivorans CJ2]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││└───

fig|365044.20.peg.3634         ⌘ NAD-dependent protein deacetylase of SIR2 family [Polaromonas naphthalenivorans CJ2]

│││││││││││││││││││││││││││││││││││││││││││││││││││││┌────

fig|420662.8.peg.3613         ⌘ NAD-dependent protein deacetylase of SIR2 family [Methylibium petroleiphilum PM1]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|595498.3.peg.907  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei Pakistan 9]

││││││││││││││││││││││││││││││││││││││││││││││││││└┤│││││││││││├─

fig|272560.3.peg.4082         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei K96243]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┼─

fig|331978.3.peg.193         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei Pasteur]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││├─

fig|320374.3.peg.2113         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei S13]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┤└─

fig|331978.4.peg.6536         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei Pasteur 52237]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└─

fig|320374.4.peg.3640  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei S13]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┤│┌─

fig|331109.3.peg.210         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei 1655]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|1247713.3.peg.3504  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei MSHR1043]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└┤┌─

fig|425067.3.peg.3019         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei 305]

│││││││││││││││││││││││││││││││││││││││││││││││││││└─┤││││││││└┤┌─

fig|320388.3.peg.2151  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia mallei SAVP1]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┤││└┼─

fig|320390.3.peg.222         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia mallei GB8 horse 4]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└─

fig|320371.4.peg.2948         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei 1710a]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|320373.5.peg.2820         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei 668]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││├─

fig|320372.3.peg.5943         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei 1710b]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─┤└┼─

fig|320388.7.peg.2385  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia mallei SAVP1]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││├─

fig|557724.3.peg.2331  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei 576]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└─

fig|536230.4.peg.2940         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia pseudomallei MSHR346]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││└─

fig|271848.8.peg.3147  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia thailandensis ATCC 700388]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌─

fig|395019.3.peg.2570  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia multivorans ATCC 17616]

│││││││││││││││││││││││││││││││││││││││││││││││││││││└───┤│││┌┴─

fig|395019.7.peg.1743         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia multivorans ATCC 17616]

││││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|513051.3.peg.4144         ⌘ NAD-dependent protein deacetylase of SIR2 family [Burkholderia multivorans CGD1]

│││││││││││││││││││││││││││││││││││││││││││││││││││││││││││┌┴─

fig|513052.3.peg.3517  ✚        ⌘ NAD-dependent protein deacetylase of SIR2 family [B